53582-00-6

Basic information

• Product Name: Cyclopropanecarboxylic acid, 2-(4-bromophenyl)-, ethyl ester, (1R,2R)-rel-
• CAS NO: 53582-00-6
• Molecular Formula: C12H13BrO2
• Molecular Weight: 269.138
• Mol File: 53582-00-6.mol
• Article Data: 28

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxylic acid, 2-(4-bromophenyl)-, ethyl ester, (1R,2R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 2-(4-bromophenyl)-, ethyl ester, (1R,2R)-rel-(53582-00-6)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 2-(4-bromophenyl)-, ethyl ester, (1R,2R)-rel-(53582-00-6)

Safety Data

• Hazardous Substances Data: 53582-00-6(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 2039-82-9 1-bromo-4-ethenyl-benzene 
• 24393-53-1 ethyl (E)-3-(4-bromophenyl)-2-propenoate 
• 36501-44-7 (Diethylamino)dimethyloxosulfonium tetrafluoroborate 
• 1200-07-3 trans-4-bromocinnamic acid 
• 24393-53-1 ethyl 4-bromocinnamate 
• 1774-47-6 trimethylsulfoxonium iodide 
• 1122-91-4 4-bromo-benzaldehyde 
• 186581-53-3 diazomethane 
• 420-04-2 CYANAMID 
• 1885-28-5 γ-(4-bromophenyl)-γ-butyrolactone 
• 100115-96-6 4-Chlor-4-(4-brom-phenyl)-buttersaeureethylester 
• 65591-79-9 (E)-1-(4-Bromo-phenyl)-pent-1-en-3-one 

Downstream Products

• 1418287-95-2 (±)-trans-O-tert-butyl-N-(2-(4-bromophenyl)cyclopropyl)carbamate 
• 71104-85-3 4-methoxy-4-(p-cyanophenyl)-1-butene 
• 114095-66-8 trans-2-(p-cyanophenyl)cyclopropanemethanol 
• 71104-65-9 cis-<2-(p-cyanophenyl)cyclopropyl>methyl acetate 
• 71104-65-9 trans-<2-(p-cyanophenyl)cyclopropyl>methyl acetate 
• 1119807-15-6 C₁₁H₉NO₂ 
• 132145-60-9 ethyl trans-2-(p-cyanophenyl)-1-cyclopropanecarboxylate 
• 90561-75-4 (1S,2R)-(+)-2-(4-bromophenyl)cyclopropyl-1-amine 
• 2137065-16-6 (cis)-2-(4-bromophenyl)cyclopropanecarboxylic acid 
• 141794-93-6 4-((1S,2S)-2-Ethoxycarbonyl-cyclopropyl)-benzoic acid ethyl ester 

Relevant articles and documents

NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE

PROBLEM TO BE SOLVED: To provide a compound that specifically activates an LPA4 receptor, and a pharmaceutical composition containing the same. SOLUTION: This invention relates to a novel lysophosphatidic acid derivative that has an agonistic action on an LPA4 receptor and is useful for the prevention and/or treatment of a disease with angiodysplasia caused by the LPA4 receptor, or a disease associated with angiopathy, or symptoms associated therewith. This invention also relates to a pharmaceutical composition containing the lysophosphatidic acid derivative. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

Iron/N-doped graphene nano-structured catalysts for general cyclopropanation of olefins

The first examples of heterogeneous Fe-catalysed cyclopropanation reactions are presented. Pyrolysis of in situ-generated iron/phenanthroline complexes in the presence of a carbonaceous material leads to specific supported nanosized iron particles, which are effective catalysts for carbene transfer reactions. Using olefins as substrates, cyclopropanes are obtained in high yields and moderate diastereoselectivities. The developed protocol is scalable and the activity of the recycled catalyst after deactivation can be effectively restored using an oxidative reactivation protocol under mild conditions. This journal is

Exploitation of Cyclopropane Carbaldehydes to Prins Cyclization: Quick Access to (E)-Hexahydrooxonine and Octahydrocyclopenta[ b]pyran

A single-step TiX4-mediated Prins-type cyclization of cyclopropane carbaldehydes with 3-buten-1-ol for the highly stereoselective construction of relatively strained (E)-hexahydrooxonines is reported. Switching the alcohol to 3-butyn-1-ol prompted a similar route, augmented by another cyclization within a nine-membered ring to afford a bicyclized product (4,4-dihalo-5-aryloctahydrocyclopenta[b]pyran). Easy transformation of the resulting geminal dihalide to a vinyl halide and a ketone further supplemented the substance of this approach.