53586-94-0Relevant academic research and scientific papers
Lithium naphthalenide induced reductive alkylation of α-cyano ketones. A general method for regiocontrol of α,α-dialkylation of ketones
Liu, Hsing-Jang,Zhu, Jia-Liang,Shia, Kak-Shan
, p. 4183 - 4186 (2007/10/03)
An efficient general method for the consecutive introduction of two alkyl groups to the α carbon of a ketone carbonyl has been developed, making use of the lithium naphthalenide induced reductive alkylation of an α-cyano ketone system as a key operation.
