535934-84-0

Upstream product

• 68716-47-2 2,4-dichlorophenylboronic acid 
• 67714-53-8 3-chloro-2,5-diethylpyrazine 

Downstream Products

• 1309978-40-2 2-(2,4-dichlorophenyl)-3,6-diethyl-5-(2-ethylbutyl)-pyrazine 
• 355836-05-4 2-sec-butylsulfanyl-5-(2,4-dichloro-phenyl)-3,6-diethylpyrazine 
• 355835-95-9 3,6-diethyl-2-(1-ethylpropoxy)-5-(2,4-dichlorophenyl)pyrazine 
• 355835-55-1 3,6-diethyl-N-propyl-N-(2-dimethylaminoethyl)-5-(2,4-dichlorophenyl)pyrazin-2-amine 
• 355835-46-0 3,6-diethyl-N,N-(2-methoxyethyl)-5-(2,4-dichlorophenyl)pyrazin-2-amine 
• 355835-47-1 3,6-diethyl-N-propyl-N-(cyclopropylmethyl)-5-(2,4-dichlorophenyl)-pyrazin-2-amine 
• 1309978-55-9 N,N-bis(cyclopropylmethyl)-5-(2,4-dichlorophenyl)-3,6-diethylpyrazin-2-amine 
• 355835-51-7 N⁽²⁾-[3,6-diethyl-5(2,4-dichlorophenyl)pyrazin-2-yl]-N⁽¹⁾,N⁽¹⁾-dimethylpropane-1,2-diamine 
• 355835-43-7 3,6-diethyl-N-[2-methoxy-1-(methoxymethyl)ethyl]-5-(2,4-dichlorophenyl)pyrazin-2-amine 
• 355835-50-6 3,6-diethyl-N-(dicyclopropylmethyl)-5-(2,4-dichlorophenyl)pyrazin-2-amine 
• 1309978-39-9 2-chloro-5-(2,4-dichlorophenyl)-3,6-diethylpyrazine 

Relevant academic research and scientific papers

Discovery of N -(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4- trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): An orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist

The design, synthesis, and structure-activity relationships of a novel series of pyrazines, acting as corticotropin releasing factor-1 (CRF-1) receptor antagonists, are described. Synthetic methodologies were developed to prepare a number of substituted p

Substituted aryl 1,4-pyrazine derivatives

Substituted aryl 1,4-pyrazine derivatives and their use in treating anxiety disorders, depression and stress related disorders are disclosed.