535969-70-1Relevant articles and documents
A novel class of apical sodium-dependent bile acid transporter inhibitors: The amphiphilic 4-oxo-1-phenyl-1,4-dihydroquinoline derivatives
Kurata, Hitoshi,Suzuki, Sayaka,Ohhata, Yasuo,Ikeda, Takuya,Hasegawa, Toru,Kitayama, Ken,Inaba, Toshimori,Kono, Keita,Kohama, Takafumi
, p. 1183 - 1186 (2004)
A series of 4-oxo-1-phenyl-1,4-dihydroquinolines possessing a linker and an ammonio moiety were synthesized and found to inhibit the apical sodium-dependent bile acid transporter (ASBT). The potency of ASBT inhibition varied with the position and length o