53608-28-9

Basic information

• Product Name: 12β-Hydroxy-5α-androstane-3,17-dione
• Synonyms: 12β-Hydroxy-5α-androstane-3,17-dione
• CAS NO: 53608-28-9
• Molecular Formula: C19H28O3
• Molecular Weight: 304.42382
• Mol File: 53608-28-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 453.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.152±0.06 g/cm3(Predicted)
• PKA: 14.33±0.60(Predicted)
• CAS DataBase Reference: 12β-Hydroxy-5α-androstane-3,17-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 12β-Hydroxy-5α-androstane-3,17-dione(53608-28-9)
• EPA Substance Registry System: 12β-Hydroxy-5α-androstane-3,17-dione(53608-28-9)

Safety Data

• Hazardous Substances Data: 53608-28-9(Hazardous Substances Data)

Relevant articles and documents

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Mass spectrometric degradation reactions of steroids with hydroxy groups in positions 12 and 17β depend on the configuration of the C-12 hydroxy group. In compounds with a 12α-hydroxy group, this group and the hydrogen in position 17α is eliminated as H2O. This reaction is followed by loss of a methyl radical. In the isomers with a 12β-hydroxy group this reaction is not possible. Here the loss of carbon 15-17 dominates the production of an ion by loss of two molecules of water. Key ions of mass 97 as well as M-44 and M-74 ions are produced by 17 keto steroids with a hydroxy group in position 12. If the rings A and B are cis-connected less specific degradation reactions are observed.