53619-72-0Relevant academic research and scientific papers
Irreversible binding of an anticancer compound (BI-94) to plasma proteins
Gautam, Nagsen,Thakare, Rhishikesh,Rana, Sandeep,Natarajan, Amarnath,Alnouti, Yazen
, p. 858 - 873 (2015)
1. We investigated the mechanisms responsible for the in vivo instability of a benzofurazan compound BI-94 (NSC228148) with potent anti-cancer activity.2. BI-94 was stable in MeOH, water, and in various buffers at pHs 2.5-5, regardless of the buffer compo
