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1-(4-methoxybenzyl)-1H-indazole is a chemical compound with the molecular formula C16H14N2O. It is a derivative of indazole, a heterocyclic aromatic organic compound consisting of a benzene ring fused to a pyrazole ring. The compound features a 4-methoxybenzyl group attached to the indazole core, which introduces a methoxy substituent at the para position of the benzene ring. This modification can influence the compound's physical and chemical properties, such as solubility, stability, and reactivity. 1-(4-methoxybenzyl)-1H-indazole is often used in the synthesis of pharmaceuticals and other organic compounds due to its unique structure and potential applications in medicinal chemistry.

5363-21-3

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5363-21-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5363-21-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,6 and 3 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5363-21:
(6*5)+(5*3)+(4*6)+(3*3)+(2*2)+(1*1)=83
83 % 10 = 3
So 5363-21-3 is a valid CAS Registry Number.

5363-21-3Downstream Products

5363-21-3Relevant academic research and scientific papers

Indazoles: Regioselective protection and subsequent amine coupling reactions

Slade, David J.,Pelz, Nicholas F.,Bodnar, Wanda,Lampe, John W.,Watson, Paul S.

supporting information; experimental part, p. 6331 - 6334 (2009/12/26)

(Chemical Equation Presented) Indazoles are unselectively protected under strongly basic conditions to give a mixture at N-1 and N-2. Under mildly acidic conditions, regioselective protection at N-2 takes place. Thermodynamic conditions lead to regioselective protection at N-1. This trend applies to various substituted indazoles. Protected 5-bromoindazoles participate in Buchwald reactions with a range of amines to generate novel derivatives.

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