53636-65-0

Basic information

• Product Name: 5-Methylpyridine-2,3-dicarboxylic acid
• Synonyms: 5-Methylpyridine-2,3-dicarboxylic acid;(5-Methyl-2,3-pyridinedicarboxylic acid)
• CAS NO: 53636-65-0
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Mol File: 53636-65-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 436.2oC at 760 mmHg
• Flash Point: 217.6oC
• Appearance: /
• Density: 1.460
• Vapor Pressure: 2.22E-08mmHg at 25°C
• Refractive Index: 1.61
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.41±0.20(Predicted)
• CAS DataBase Reference: 5-Methylpyridine-2,3-dicarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Methylpyridine-2,3-dicarboxylic acid(53636-65-0)
• EPA Substance Registry System: 5-Methylpyridine-2,3-dicarboxylic acid(53636-65-0)

Safety Data

• Hazardous Substances Data: 53636-65-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H7NO4/c1-4-2-5(7(10)11)6(8(12)13)9-3-4/h2-3H,1H3,(H,10,11)(H,12,13)

Upstream product

• 105151-48-2 diethyl 5-methylpyridine-2,3-dicarboxylate 
• 104098-48-8 imazapic 
• 112110-16-4 5-methyl-2,3-pyridinedicarboxylic acid dimethyl ester 
• 612-58-8 3-methylquinoline 
• 7732-18-5 water 
• 20668-26-2 3,6-dimethylquinoline 
• 75457-13-5 8-hydroxy-3-methylquinoline 

Downstream Products

• 104098-48-8 imazapic 
• 105151-48-2 diethyl 5-methylpyridine-2,3-dicarboxylate 

Relevant articles and documents

Preparation method of nitrogen-containing aromatic dicarboxylic acid

The invention discloses a preparation method of nitrogen-containing aromatic dicarboxylic acid. The method includes: taking quinoline, isoquinoline, benzimidazole or benzotriazole and a derivative thereof as the raw materials, adopting oxone as the oxidant, employing a metal salt as the catalyst and using inorganic acid as the medium, adding a phase transfer reagent, and carrying out reaction to obtain nitrogen-containing aromatic dicarboxylic acid. The reagents used by the method are high in stability, convenient for transportation and storage, the operation is simple, the conditions are easily controllable, and the price is low, at the same time, the catalytic effect is good, the yield is high, and waste liquid treatment is easy, therefore the method is convenient for industrial large-scale production.

Preparation method for imidazolinone compound

The invention provides a preparation method for an imidazolinone compound, belongs to the technical field of organic synthesis, and can solve the problems that a large amount of wastewater is producedand the content of impurities in the product is high in the existing process for preparing the imidazolinone compound. According to the preparation method for the imidazolinone compound provided by the invention, a solution of 5-alkyl pyridine-2,3-phthalate is synthesized from ammonium carbonate; the steps of adding water, extracting, refining and the like are avoided in post-treatment; the obtained solution of the 5-alkyl pyridine-2,3-phthalate is used for subsequent reaction; and the wastewater is not produced. Then, a catalyst is added in the process of preparing 5-alkyl pyridine-2,3-dimethylbenzene anhydride, and the pH is controlled in the subsequent reaction process, so that the production of the impurities can be avoided, and the product purity is improved. The imidazolinone compound prepared by the method provided by the invention can be used as a high-efficiency herbicide.

Method for the preparation of 2,3-pyridine-dicarboxylic acids and derivatives thereof

There is provided an improved process for the preparation of substituted and unsubstituted 2,3-pyridinedicarboxylic acids in significantly enhanced yield by the nitric acid oxidation of the appropriately substituted quinoline precursor in the presence of a catalytic amount of Manganese.