5365-17-3

Usage

Appearance

Colorless to pale yellow liquid The compound's physical state and color at room temperature.

Odor

Strong bromine The compound has a noticeable and pungent bromine smell.

Usage

Intermediate in pharmaceuticals and agrochemicals It is mainly used as an intermediate compound in the synthesis of various pharmaceuticals and agrochemicals.

Usage

Organic synthesis The compound is also used in organic synthesis for creating other organic compounds.

Usage

Building block in complex organic compounds It serves as a building block for the preparation of more complex organic compounds.

Reactivity

Highly reactive The compound is known for its high reactivity, which necessitates careful handling.

Hazards

Corrosive The compound has corrosive properties, which can cause damage to materials and surfaces it comes into contact with.

Hazards

Toxic The compound is toxic, and exposure can pose health risks. It should be handled with care to avoid harm.

Upstream product

• 5398-65-2 1,1-dibromo-2-vinylcyclopropane 
• 5398-70-9 1,1-dibromo-2-butylcyclopropane 
• 22084-99-7 2,2-dibromocyclopropane-1-methanol 

Downstream Products

• 31191-77-2 (1SR,2RS)-2-bromocyclopropanecarboxylic acid 

Relevant academic research and scientific papers

Thermodynamic control of diastereoselectivity in the formal nucleophilic substitution of bromocyclopropanes

(Figure Presented) A new, general, and chemoselective protocol for the formal nucleophilic substitution of 2-bromocyclopropylcarboxamides is described. A wide range of alcohols and phenols can be employed as pronucleophiles in this transformation, providi

Synthesis of novel precursors of calicene and 7-methylcalicene

Cyclopent-2-en-1-one is a versatile electrophilic cyclopentadiene equivalent in reactions with 1-bromo-1-lithiocyclopropanes. The synthetic sequence (outlined in Scheme 1) has been applied to the synthesis of functionalized 7-X-7,8-dihydrocalicenes 13c (Scheme 3) and 13d (Scheme 4). 7- Bromo-7,8-dihydrocalicene (13d) is considered to be a promising precursor of the so far unknown parent calicene (2). A similar sequence has been realized for 7-(chloromethyl)-7,8-dihydrocalicene (21a, Scheme 5) which, under appropriate conditions, could give 7-methylcalicene (16).

Unusual selectivity in the oxidative functionalization of gem-dibromocyclopropanes

Oxidation of gem-dibromocyclopropanes with chromium trioxide in acetic acid or a number of other reagents is generally slower than that of the corresponding cyclopropane; in a number of cases moderate yields of products are obtained but these show unexpected oxidation patterns.

6-(Substituted-cycloalkylcarboxamide) penicillanic acids

Penicillins of the formula SPC1 Or a pharmaceutically-acceptable, nontoxic salt thereof, Wherein R1 and R2 are the same or different and each is hydrogen, fluorine, chlorine or bromine; or when R2 is hydrogen, R1 can also be cyano, hydroxyl, azido, amino or nitro; or R1 and R2 are bonded to a ring carbon atom and constitute a single oxygen atom; R3 is hydrogen, methyl, chlorine, bromine, cyano, methoxy or carboxyl; and n is 2 to 7; Are useful for their antibacterial activity.