53663-33-5Relevant academic research and scientific papers
TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS
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, (2008/06/13)
Tri-and tetra-substituted guanidines which exhibit a high binding affinity to phencyclidine (PCP) receptors and, more preferably, low affinity to the brain sigma receptors. These guanidine derivatives act as non-competitive inhibitorsSTATEMENT AS TO RIGHT
A convenient syntheses of some new substituted guanidines
Ahmad, S. S.,Haider, S. I.,Fatima, I.
, p. 1861 - 1864 (2007/10/02)
The cyanamides of 2,6-dimethylaniline, N-methyl-α, β-naphthylamines, 2-methylpiperidine and indoline yielded their respective guanido derivatives on treatment with dry ammonia and their structures have been characterized through spectral studies.
Some Extensions of von Braun (BrCN) Reaction on Organic Bases
Siddiqui, Salimuzzaman,Siddiqui, Bina S.
, p. 1049 - 1052 (2007/10/02)
Some extensions of von Braun cyanogen bromide reaction have been undertaken on conessine, isoconessine and two simpler bases, dimethyl α-naphthyl amine and diethyl amine.The monocyanamides of conessine and isoconessine yielded acid amides, aminoderivatives (diamines) and guanido derivatives on careful hydrolysis, reduction and treatment with ammonia, respectively.The simpler bases also formed the acid amides and diamines but failed to give the guanido derivatives under the conditions employed for conessine series.Diamines of all these bases yielded carbinol amines on reaction with nitrous acid. - Key words: von Braun Cyanogen Bromide Reaction
