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Benzene, 1-(4-bromobutoxy)-4-(1,1-dimethylethyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

53669-73-1

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53669-73-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 53669-73-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,6,6 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 53669-73:
(7*5)+(6*3)+(5*6)+(4*6)+(3*9)+(2*7)+(1*3)=151
151 % 10 = 1
So 53669-73-1 is a valid CAS Registry Number.

53669-73-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-bromobutoxy)-4-tert-butylbenzene

1.2 Other means of identification

Product number -
Other names 1-(4-bromobutoxy)-4-(1,1-dimethylethyl)-benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53669-73-1 SDS

53669-73-1Relevant articles and documents

Viologen-cucurbituril host/guest chemistry - redox control of dimerizationversusinclusion

Asfari, Zouhair,Benyettou, Farah,Dalvand, Parastoo,Elhabiri, Mourad,Nchimi Nono, Katia,Olson, Mark A.,Platas-Iglesias, Carlos,Shetty, Dinesh,Trabolsi, Ali

, p. 29543 - 29554 (2021/10/08)

Two calix[4]arene systems,C234+andC244+- where 2 corresponds to the number of viologen units and 3-4 corresponds to the number of carbon atoms connecting the viologen units to the macrocyclic core - have been synthesized and led to t

Dual target ligands with 4-tert-butylphenoxy scaffold as histamine H3 receptor antagonists and monoamine oxidase B inhibitors

?a?ewska, Dorota,Doroz-P?onka, Agata,Frank, Annika,Kaleta, Maria,Karcz, Tadeusz,Kie?-Kononowicz, Katarzyna,Latacz, Gniewomir,Olejarz-Maciej, Agnieszka,Reiner, David,Stark, Holger,Zygmunt, Ma?gorzata

, (2020/05/22)

Dual target ligands are a promising concept for the treatment of Parkinson’s disease (PD). A combination of monoamine oxidase B (MAO B) inhibition with histamine H3 receptor (H3R) antagonism could have positive effects on dopamine re

Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands

Szczepańska, Katarzyna,Karcz, Tadeusz,Mogilski, Szczepan,Siwek, Agata,Kuder, Kamil J.,Latacz, Gniewomir,Kubacka, Monika,Hagenow, Stefanie,Lubelska, Annamaria,Olejarz, Agnieszka,Kotańska, Magdalena,Sadek, Bassem,Stark, Holger,Kie?-Kononowicz, Katarzyna

supporting information, p. 223 - 234 (2018/05/09)

As a continuation of our search for novel histamine H3 receptor ligands, a series of twenty four new tert-butyl and tert-pentyl phenoxyalkylamine derivatives (2?25) was synthesized. Compounds with three to four carbon atoms alkyl chain spacer were evaluated for their binding properties at human histamine H3 receptor (hH3R). The highest affinities were observed for 4-pyridyl derivatives 4, 10, 16 and 22 (Ki = 16.0–120 nM). As it has been shown in docking studies, those specific heteroaromatic 4-N piperazine substituents might interact with one of the key receptor interacting amino acids. Moreover, the most promising compounds exhibited anticonvulsant activity in the maximal electroshock-induced seizure (MES) model in mice. Furthermore, the blood-brain barrier penetration, the functional H3R antagonist potency as well as the pro-cognitive properties in the passive avoidance test were demonstrated for compound 10. In order to estimate drug-likeness of compound 10, in silico and experimental evaluation of metabolic stability in human liver microsomes was performed. In addition, paying attention to the results obtained within this study, the 4-pyridyl-piperazino moiety has been established as a new bioisosteric piperidine replacement in H3R ligands.

ω-Phenoxyalkyl substituted bis(indenyl)zirconium dichloride complexes as catalysts for homogeneous ethylene polymerization

Ahmad, Khalil,Alt, Helmut G.

, p. 63 - 71 (2015/06/02)

Nine bis(indenyl)zirconium dichloride complexes of the type [C9H6-(CH2)n-O-Ar]2ZrCl2 (n = 3-5; Ar = Ph, t-Bu-Ph) were synthesized, characterized, activated with methylalumoxane (MAO) and tested for ethylene polymerization. Structure-property-relationship studies showed that the activities of the catalysts depend on the length of the bridging chain between the indenyl and the phenoxy group as well as on the bulk at the phenoxy substituent. A t-Bu substituent at the ortho position of the phenoxy group (5a/MAO) gives a much higher catalyst activity (27,500 kg PE/mol cat h) than the isomer 8a/MAO with a t-Bu substituent at the para position of the phenoxy group (16,700 kg PE/mol cat h). Obviously substituents in the ortho position of the phenyl ring generate a bulkier catalyst cation and this can keep the MAO anion at a further distance to allow easier ethylene coordination and chain growth in the polymerization steps. The mono substituted bis(indenyl) complex (C9H7)[C9H6-(CH2)4-O-4-t-Bu]ZrCl2 shows lower activity (11,700 kg PE/mol cat h) than 8a indicating that the electronic effect is dominating in this type of catalysts.

Discovery of highly potent novel antifungal azoles by structure-based rational design

Wang, Wenya,Sheng, Chunquan,Che, Xiaoying,Ji, Haitao,Cao, Yongbing,Miao, Zhenyuan,Yao, Jianzhong,Zhang, Wannian

supporting information; experimental part, p. 5965 - 5969 (2010/07/04)

On the basis of the active site of lanosterol 14α-demethylase from Candida albicans (CACYP51), a series of new azoles were designed and synthesized. All the new azoles show excellent in vitro activity against most of the tested pathogenic fungi, which represent a class of promising leads for the development of novel antifungal agents. The MIC80 value of compounds 8c, 8i and 8n against C. albicans is 0.001 μg/mL, indicating that these compounds are more potent than fluconazole, itraconazole and voriconazole. Flexible molecular docking was used to analyze the structure-activity relationships (SARs) of the compounds. The designed compounds interact with CACYP51 through hydrophobic, van der Waals and hydrogen-bonding interactions.

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