536737-35-6

Upstream product

• 536737-40-3 (R)-3-Methyl-4-((S)-1-methyl-prop-2-ynyl)-tetrahydro-pyran-2-one 
• 536737-41-4 (3R,4S)-3-(2-Hydroxy-ethyl)-2,4-dimethyl-hex-5-ynoic acid methoxy-methyl-amide 
• 536737-39-0 2-{(1R,2S)-1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-methyl-4-trimethylsilanyl-but-3-ynyl}-2-methyl-malonic acid diethyl ester 
• 536737-38-9 2-{(1R,2S)-1-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-methyl-4-trimethylsilanyl-but-3-ynyl}-malonic acid diethyl ester 

Relevant academic research and scientific papers

An efficient synthesis of optically active (2R,3R)-2-methyl-3-[(1R)-1-methylprop-2-enyl]cyclopentanone, a useful chiral building block for synthesis of vitamin D and steroids

An efficient synthesis of optically active (2R,3R)-2-methyl-3-[(1R)-1-methylprop-2-enyl]cyclopentanone, a useful chiral building block for synthesis of vitamin D and steroids, has been developed starting from readily accessible optically active secondary propargyl phosphate (R)-2, where the asymmetric Michael addition of a chiral allenyltitanium to alkylidenemalonate 3 is a key reaction.