536743-10-9Relevant academic research and scientific papers
Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies
Huang, Yen-Lin,Lin, Chyun-Feng,Lee, Yi-Jen,Li, Wei-Wei,Chao, Ting-Chou,Bacherikov, Valeriy A.,Chen, Kuo-Tung,Chen, Chin-Ming,Su, Tsann-Long
, p. 145 - 157 (2007/10/03)
A series of non-classical antifolates, namely 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines (25a-i) and 2,4-diamino-(N-phenylpyrrolidin-3-yl)-6(5H)-oxopyrimidines (26a,b,c,f,h,i) was synthesized and evaluated for their in vitro cytotoxicity. React
