53681-51-9 Usage
Uses
Used in Pharmaceutical Industry:
6-Amino-1-benzyl-3-methyl-1H-pyrimidine-2,4-dione is used as an antineoplastic agent for its potential to combat cancer. Its pharmacological properties are being studied to understand its mechanism of action and efficacy in treating neoplastic diseases.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-Amino-1-benzyl-3-methyl-1H-pyrimidine-2,4-dione serves as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the development of new pharmaceuticals and therapeutic agents.
Used in Drug Development:
6-Amino-1-benzyl-3-methyl-1H-pyrimidine-2,4-dione is utilized in drug development for its potential to contribute to the creation of novel therapeutics. Its role as an intermediate in organic synthesis facilitates the exploration of new drug candidates and the enhancement of existing medications.
Check Digit Verification of cas no
The CAS Registry Mumber 53681-51-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,6,8 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 53681-51:
(7*5)+(6*3)+(5*6)+(4*8)+(3*1)+(2*5)+(1*1)=129
129 % 10 = 9
So 53681-51-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H13N3O2/c1-14-11(16)7-10(13)15(12(14)17)8-9-5-3-2-4-6-9/h2-7H,8,13H2,1H3
53681-51-9Relevant academic research and scientific papers
Synthesis and analytical profile of the new potent antibronchospastic agent 7-[(2,2-dimethyl)propyl]-1-methyl xanthine
Agostini,Bonacchi,Coppini,Di Marco,Paoli,Toja
, p. 684 - 688 (2007/10/02)
7-[(2,2-Dimethyl)propyl]-1-methyl xanthine (CAS 155006-67-0, MX2/120) is a new potent antibronchospastic agent with negligible side effects. The synthesis involves the alkylation of 3-benzyl-1-methyl xanthine with neopentyl bromide followed by removal of
Structure-activity relationships in a series of xanthine derivatives with antibronchoconstrictory and bronchodilatory activities
Merlos,Gomez,Vericat,Bartroli,Garcia-Rafanell,Forn
, p. 653 - 658 (2007/10/02)
Thirty-one 1,3,7,8-substituted xanthine derivatives have been synthesized and evaluated for bronchodilator and anti-bronchoconstrictory activities in in vitro tracheal relaxation and in vivo bronchospasm inhibition models. Activity tests have been complemented with phosphodiesterase inhibition and toxicological data. Structure-activity relationships are discussed. Compound 21 (1,3-diisobutyl-8-methylxanthine) has been selected for further pharmacological development because of its good activity profile and favourable therapeutic index, which is 14- and 38-fold greater than that of theophylline and IBMX, respectively.
