53694-74-9Relevant academic research and scientific papers
AN UNUSUAL REACTION OF CIS-6-HYDROPEROXY-5-HYDROXY-5,6-DIHYDROTHYMINE WITH ASCORBIC ACID
Itahara, Toshio
, p. 4079 - 4080 (1987)
When two solutions of cis-6-hydroperoxy-5-hydroxy-5,6-dihydrothymine and ascorbic acid in deuterium oxide were mixed, chemically induced dynamic nuclear polarization was observed.The reaction gave N-formyl-N'-pyruvylurea.
Oxidation of Thymines by Peroxosulfate Ions in Water
Itahara, Toshio,Fujii, Yukiko,Tada, Miki
, p. 3421 - 3424 (2007/10/02)
Oxidation of thymines by sodium peroxodisulfate in water at 85 deg C gave the corresponding 5-(hydroxymethyl)uracils and 5-formyluracils.The reaction may proceed via thymine cation radicals.On the other hand, oxidation of thymines by potassium peroxomonosulfate in water gave the corresponding cis-5,6-dihydroxy-5,6-dihydrothymines and 5-hydroxy-5-methylbarbituric acids.Furthermore, treatment of thymine with both potassium peroxomonosulfate and hydrogen peroxide in water gave cis-6-hydroperoxy-5-hydroxy-5,6-dihydrothymine.
