536976-77-9

Upstream product

• 536976-76-8 2-[1-(2-bromo-ethyl)-allyl]-4-(tert-butyl-diphenyl-silanyloxy)-pyrrolidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 536976-78-0 (2R,4R)-4-[3-(4-Benzyloxy-3-methoxy-phenyl)-propionyloxy]-2-(3-bromo-1-methoxycarbonyl-propyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 536976-79-1 (6R,7aR)-6-[3-(4-Benzyloxy-3-methoxy-phenyl)-propionyloxy]-hexahydro-pyrrolizine-1-carboxylic acid methyl ester 

Relevant academic research and scientific papers

First total synthesis of a new pyrrolizidine alkaloid, amphorogynine A

An efficient and stereodefined strategy is described for the first asymmetric synthesis of a new type of pyrrolizidine alkaloids, amphorogynine A and its 1-epi-isomer. The key 2,4-disubstituted pyrrolidine ring was constructed by elaboration of the chiral