5371-86-8Relevant articles and documents
Acetate selective fluorescent turn-on sensors derived using Vitamin B6 cofactor pyridoxal-5-phosphate
Sharma, Darshna,Kuba, Aman,Thomas, Rini,Ashok Kumar,Kuwar, Anil,Choi, Heung-Jin,Sahoo, Suban K.
, p. 110 - 115 (2016)
Two new Schiff base receptors have been synthesized by condensation of pyridoxal-5-phosphate with 2-aminophenol (L1) or aniline (L2). In DMSO, the receptors showed both chromogenic and 'turn-on' fluorescence responses selectively in the presence of AcO- and F-. However, in mixed DMSO-H2O medium, the receptors showed AcO- selective 'turn-on' fluorescence without any interference from other tested anions including F-. The detection limit for AcO- was found to be 7.37 μM and 22.9 μM using the receptors L1 and L2, respectively.
Biomimetic chirality sensing with pyridoxal-5′-phosphate
Pilicer, Samantha L.,Bakhshi, Pegah R.,Bentley, Keith W.,Wolf, Christian
, p. 1758 - 1761 (2017/02/15)
Pyridoxal-5′-phosphate (PLP) is introduced to a biomimetic indicator displacement assay for simultaneous determination of the absolute configuration, enantiomeric composition and concentration of unprotected amino acids, amino alcohols and amines. The chiroptical assay is based on fast imine metathesis with a PLP aryl imine probe to capture the target compound for circular dichroism and fluorescence sensing analysis. The substrate binding yields characteristic Cotton effects that provide information about the target compound ee and the synchronous release of the indicator results in a nonenantioselective off-on fluorescence response that is independent of the enantiomeric sample composition and readily correlated to the total analyte concentration.