Oxfendazole is a broad spectrum benzimidazole anthelmintic approved
for veterinary use. It is effective to protect livestock and poultry
from most of the parasites such as roundworms, tapeworms, strongyles
and pinworms. The drug is mainly applied in the form of pills,
tables, drenches and bolus, etc. especially for horses, goats,
cattle, sheep, etc.
The drug functions on parasites by binding to tubulin, which is a
structural protein of microtubules. In the parasites the blocking of
microtubules interferes with the uptake of glucose, which ultimately
empties the glycogen reserves. This blocks the whole energy
management mechanism of the parasites and eventually leads to death.
Synanthic Veterinary (Syntex).
A metabolite of Fenbendazole (F246750).
ChEBI: A member of the class of benzimidazoles that is fenbendazole in which the sulfur has been oxidised to the corresponding sulfoxide.