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5-Hydroxymethyl-3-(4-methoxyphenyl)-1,2,4-oxadiazole is a chemical compound with the molecular formula C9H9N2O3. It is a derivative of the 1,2,4-oxadiazole heterocycle, which is a five-membered ring containing two oxygen atoms and one nitrogen atom. The compound features a hydroxymethyl group (-CH2OH) at the 5-position and a 4-methoxyphenyl group (-OCH3 attached to a phenyl ring) at the 3-position. This molecule is known for its potential applications in various fields, such as pharmaceuticals and materials science, due to its unique structure and properties. It can be synthesized through various chemical reactions and is often used as a building block for the development of new compounds with specific biological activities or material properties.

5372-39-4

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5372-39-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5372-39-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,7 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5372-39:
(6*5)+(5*3)+(4*7)+(3*2)+(2*3)+(1*9)=94
94 % 10 = 4
So 5372-39-4 is a valid CAS Registry Number.

5372-39-4Relevant academic research and scientific papers

One-step protection-free synthesis of 3-aryl-5-hydroxyalkyl-1,2,4- oxadiazoles as building blocks

Neves Filho, Ricardo A. W.,Da Silva-Alves, Diana C. B.,Dos Anjos, Janaina V.,Srivastava, Rajendra M.

supporting information, p. 2596 - 2602 (2013/07/26)

A simple and straightforward synthesis of 3-aryl-5-hydroxyalkyl-1,2,4- oxadiazoles is described. The reaction among arylamidoximes, ethyl glycolate or ethyl lactate, and potassium carbonate in refluxing toluene afforded the desired 1,2,4-oxadiazoles in moderate to good yields. The synthesis has been accomplished in a single step, avoiding protection-deprotection protocols. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.

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