53730-27-1Relevant academic research and scientific papers
Ascochlorin derivatives from the leafhopper pathogenic fungus Microcera sp. BCC 17074
Isaka, Masahiko,Yangchum, Arunrat,Supothina, Sumalee,Laksanacharoen, Pattiyaa,Jennifer Luangsa-Ard,Hywel-Jones, Nigel L
, p. 47 - 51 (2015)
Two new ascochlorin derivatives, nectchlorins A (1) and B (2), together with eight known compounds (3-10), were isolated from cultures of the leafhopper pathogen Microcera sp. BCC 17074. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. The absolute configuration of 2 was determined by application of the modified Mosher's method. The absolute configuration of LL-Z 1272α epoxide (9), which is a plausible biosynthetic precursor of ascochlorins, was established by chemical correlations. Cytotoxic activities of these ascochlorin derivatives were evaluated.
