53730-40-8

Upstream product

• 53101-55-6 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-acetic Acid 
• 72295-13-7 rac.-3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-acetonitrile 
• 53101-68-1 3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-2,6-diol 
• 53101-72-7 rac-3,4-dihydro-6-acetyloxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-ol 
• 77286-97-6 (+)-(R)-methyl(6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)acetate 

Relevant academic research and scientific papers

Cardioprotective tocopherol analogs

This invention relates to quaternary ammonium salts of certain 2H-1-benzopyran derivatives, to the intermediates and processes useful for their preparation, to their free-radical scavenger and cellular protective properties and to their end-use application as therapeutic agents.

Cardioselective ammonium, phosphonium, and sulfonium analogues of α- tocopherol and ascorbic acid that inhibit in vitro and ex vivo lipid peroxidation and scavenge superoxide radicals

Analogues of α-tocopherol and ascorbic acid with permanently cationic substituents, i.e., phosphonium (8, 9), sulfonium (11), acylhydrazinium (13, 14), and ammonium (1, 16, 21), were synthesized, and the 2R and 2S enantiomers of the α-tocopherol analogues

Antioxidant chroman compounds

The (6-hydroxy-chroman-2-yl) acetic or carboxylic acid derivatives useful as antioxidants and a method for preparing these derivatives from hydroquinones and intermediates in this synthesis as well as the use of these derivatives as intermediates in the preparation of optically active alpha-tocopherol.