Basic information

Product Name: TRIMAZOSIN HYDROCHLORIDE
Synonyms: TRIMAZOSIN HYDROCHLORIDE;Trimazosin HCl;Trimazosin hydrochlorid-1-wasser;Trimazosin hydrochloride monohydrate;Trimazosin monohydrochloride monohydrate;Unii-827T79Ile7;4-(4-AMino-6,7,8-triMethoxy-2-quinazolinyl)-1-piperazinecarboxylic Acid 2-Hydroxy-2-Methylpropyl Ester Hydrochloride
CAS NO:53746-46-6
Molecular Formula: C20H29N5O6.ClH.H2O
Molecular Weight: 489.954
EINECS: N/A
Product Categories: N/A
Mol File: 53746-46-6.mol

Chemical Properties

Melting Point: 166-169° (dec)
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
CAS DataBase Reference: TRIMAZOSIN HYDROCHLORIDE(CAS DataBase Reference)
NIST Chemistry Reference: TRIMAZOSIN HYDROCHLORIDE(53746-46-6)
EPA Substance Registry System: TRIMAZOSIN HYDROCHLORIDE(53746-46-6)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 53746-46-6(Hazardous Substances Data)

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Usage
SDS
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53746-46-6 Usage

Uses

Used in Pharmaceutical Industry:
Trimazosin hydrochloride is used as a therapeutic agent for the treatment of various medical conditions, particularly those involving the urinary system. It functions by blocking the α1-adrenergic receptors, leading to vasodilation and reduced peripheral resistance, which in turn helps alleviate symptoms associated with benign prostatic hyperplasia (BPH) and other related conditions.
Additionally, its longer duration of action and absence of first-dose hypotensive effects make it a preferred choice for patients who require a more stable and predictable treatment regimen.

Originator

Pfizer (USA)

Check Digit Verification of cas no

The CAS Registry Mumber 53746-46-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,7,4 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 53746-46:
(7*5)+(6*3)+(5*7)+(4*4)+(3*6)+(2*4)+(1*6)=136
136 % 10 = 6
So 53746-46-6 is a valid CAS Registry Number.

53746-46-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	(2-hydroxy-2-methylpropyl) 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate,hydrate,hydrochloride

1.2 Other means of identification

Product number	-
Other names	Trimazosin hydrochloride monohydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53746-46-6 SDS

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53746-46-6Downstream Products

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