53768-14-2Relevant academic research and scientific papers
Carbocyclic Construction by the Sigmatropic Rearrangement of Cyclic Sulfonium Ylides. A New Entry for the Stereoselective Synthesis of Substituted Cyclohexanones
Kido, Fusao,Yamaji, Kazuo,Sinha, Subhash C.,Abiko, Toshiya,Kato, Michiharu
, p. 7697 - 7714 (1995)
The rhodium(II)-catalyzed cyclization of acyclic α-diazo-β-keto esters 1c,d provided stereoselectively the highly substituted cyclohexanones 3c,d respectively, by the sigmatropic rearrangement via stereocontrolled nine-membered allylsulfonium ylides 2c,d.Further elaboration of 3d toward the cyclohexanone 36 accomplished asymmetric formal syntheses of the representative elemanoids, 37 and 38.The compound 3c was transformed into the cyclohexanone 34a and cyclohexene 43, which could serve as the key intermediates for the synthesis of natural products possessing contigously cis-arranged trimethylcyclohexanone and its related moieties, respectively.
Total Synthesis of (-)-Chiloscyphone, Sesquiterpenoid Isolated from the Liverwort. Absolute Configuration of (-)-Chiloscyphone and (+)-Chiloscypholone
Tori, Motoo,Hasebe, Takeshi,Asakawa, Yoshinori
, p. 1706 - 1712 (2007/10/02)
The absolute configurations of (-)-chiloscyphone and (+)-chiloscypholone isolated from the liverwort Chiloscyphus polyanthos and C. pallescens respectively, have been determined by the total synthesis of the optically active compound.The 1,4-addition of v
Total Sythesis of Liverwort Sesquiterpene Ketone (+/-)-Chiloscyphone via Intramolecular Aldol Condensation
Tori, Motoo,Hasebe, Takeshi,Asakawa, Yoshinori
, p. 2059 - 2060 (2007/10/02)
(+/-)-Chiloscyphone, a sesquiterpene ketone isolated from the liverwort, has been synthesized starting from 3,4-dimethyl-2-cyclohexen-1-one via intramolecular aldol condensation.
