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"3-{[(2-chlorophenyl)amino]methyl}-1,3-thiazolidine-2,4-dione" is a complex organic compound with the molecular formula C10H8ClN3O2S. It features a 1,3-thiazolidine-2,4-dione core, which is a five-membered heterocyclic ring containing sulfur, oxygen, and nitrogen atoms. The compound has a 2-chlorophenyl group attached to the nitrogen atom of the thiazolidine ring, and an aminomethyl group connected to the 3-position of the thiazolidine. This structure is significant in medicinal chemistry, as it is a key component of certain drugs, such as the antiplatelet agent Clopidogrel. The chlorine atom in the 2-chlorophenyl group and the amide groups in the 2,4-dione part of the molecule contribute to its pharmacological properties, making it an important molecule in the development of therapeutic agents.

5377-23-1

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Basic information
1. Product Name: 3-{[(2-chlorophenyl)amino]methyl}-1,3-thiazolidine-2,4-dione
2. Synonyms: 2,4-thiazolidinedione, 3-[[(2-chlorophenyl)amino]methyl]-; 3-[(2-Chloro-phenylamino)-methyl]-thiazolidine-2,4-dione; 3-{[(2-Chlorophenyl)amino]methyl}-1,3-thiazolidine-2,4-dione
3. CAS NO:5377-23-1
4. Molecular Formula: C₉H₁₃NO
5. Molecular Weight: 256.7087
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 435.7°C at 760 mmHg
3. Flash Point: 217.3°C
4. Appearance: N/A
5. Density: 1.517g/cm³
6. Vapor Pressure: 8.57E-08mmHg at 25°C
7. Refractive Index: 1.689
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: 3-{[(2-chlorophenyl)amino]methyl}-1,3-thiazolidine-2,4-dione(CAS DataBase Reference)
11. NIST Chemistry Reference: 3-{[(2-chlorophenyl)amino]methyl}-1,3-thiazolidine-2,4-dione(5377-23-1)
12. EPA Substance Registry System: 3-{[(2-chlorophenyl)amino]methyl}-1,3-thiazolidine-2,4-dione(5377-23-1)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 5377-23-1(Hazardous Substances Data)

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5377-23-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5377-23-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,7 and 7 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 5377-23:
(6*5)+(5*3)+(4*7)+(3*7)+(2*2)+(1*3)=101
101 % 10 = 1
So 5377-23-1 is a valid CAS Registry Number.

5377-23-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	3-[(2-chloroanilino)methyl]-1,3-thiazolidine-2,4-dione

1.2 Other means of identification

Product number	-
Other names	6-methyl-2-propylpyridin-3-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5377-23-1 SDS

5377-23-1Upstream product

1117686-46-0 3-(Benzyloxy)-6-methyl-2-propylpyridine

5377-23-1Downstream Products

1117685-81-0 4-(6-methyl-2-propylpyridin-3-yloxy)-N-(3,4,5-trimethoxyphenyl)pyridin-2-amine

5377-23-1Relevant academic research and scientific papers

CHEMICAL COMPOUNDS-821

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Page/Page column 65, (2009/03/07)

The invention relates to chemical compounds of the formula (I), or pharmaceutically acceptable salts thereof, which possess ALK5 (TGFβR1) inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the

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