5377-40-2

Upstream product

• 10176-13-3 1-chloro-2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethane 
• 1005500-55-9 N-(2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethyl)phthalimide 
• 1611-07-0 3,5-Di-tert-butyl-4-hydroxyphenylacetonitrile 

Downstream Products

• 224564-30-1 3-benzyloxy-1-(2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethyl)-2-methyl-4(1H)-pyridinone 
• 662-50-0 heptafluorobutyramide 
• 1233487-96-1 C₂₇H₃₈N₆O₅ 
• 1233488-11-3 N-(4-cyanophenyl)-N₄-(3,5-di-tert-butyl-4-hydroxyphenethyl)succinamide 
• 1233487-88-1 C₂₆H₃₇N₅O₅ 
• 1217276-11-3 (2E)-2-(1-(3,5-di-tert-butyl-4-hydroxyphenethylamino)ethylidene)-6-(1-(3,5-di-tert-butyl-4-hydroxyphenethylimino)ethyl)-7,9-dihydroxy-8,9b-dimethyldibenzo[b,d]furan-1,3(2H,9bH)-dione 
• 1217276-05-5 (E)-6-acetyl-2-(1-(3,5-di-t-butyl-4-hydroxyphenethylamino)ethylidene)-7,9-dihydroxy-8,9b-dimethyldibenzo[b,d]furan-1,3(2H,9bH)-dione 

Relevant academic research and scientific papers

Synthesis and evaluation of new N6-substituted adenosine-5′-N-methylcarboxamides as A3 adenosine receptor agonists

A number of N6-substituted adenosine-5′-N-methylcarboxamides were synthesised and their pharmacology, in terms of their receptor affinity, selectivity and cardioprotective effects, were explored. The first series of compounds, 4a-4f and 5a-5f,

Synthesis and antioxidant activities of 3,5-dialkoxy-4-hydroxycinnamamides

A series of 3,5-dialkoxy-4-hydroxycinnamamides 6 and 7 was synthesized, and their antioxidant activity was assessed using the thiobarbituric acid reactive substance (TBARS) assay. Interestingly, cinnamamides with longer alkoxy groups on the C-3 and C-5 positions display enhanced inhibition, and most of the compounds in the series tested exhibit excellent lipid peroxidation inhibitory activities. Some cinamamides bearing hexyloxy or 2,6-di-tert-butyl-4-methyl phenol groups have submicromolar inhibitory activities.

Synthesis and inhibitory activity of alkyl(hydroxyaryl)amines

The reaction of ω-(4-hydroxyaryl)haloalkanes with various nitrogen-containing agents afforded primary, secondary, and tertiary amino derivatives of 2,6-dialkylphenols. For the compounds synthesized, the reaction rate constants with peroxide radicals were

Reactions of perfluoro(2-methylpent-2-ene) and perfluoro(5-azanon-4-ene) with primary amines containing a 2,6-di-tert-butylphenol fragment

Reactions of perfluoro(2-methylpent-2-ene) and perfluoro(5-azanon-4-ene) with 4-(2-aminoethyl)-2,6-di-tert-butylphenol and 4-(3-aminopropyl)-2,6-di-tert- butylphenol in acetonitrile in the presence of triethylamine gave the corresponding azetidine, 1,2-dihydroazete, and 1,2-dihydro-1,3-diazete derivatives, respectively. The reaction mechanisms, role of triethylamine, and factors affecting the intramolecular nucleophilic cyclization process are discussed.