537703-97-2

Upstream product

• 537703-93-8 (3S,4'S)-2-benzyl-3-(2',2'-dimethyl-1',3'-dioxolan-4'-yl)-3,4,5,6-tetrahydro-2H-1,2-oxazin-4-one 
• 227622-58-4 (3S,4′S)-2-benzyl-3-(2′,2′-dimethyl-1′,3′-dioxolan-4′-yl)-4-methoxy-3,6-dihydro-2H-1,2-oxazine 
• 537703-94-9 (3R,4S)-2-Benzyl-3-((S)-2,2-dimethyl-[1,3]dioxolan-4-yl)-[1,2]oxazinan-4-ol 

Relevant academic research and scientific papers

Synthesis of enantiopure amino polyols and pyrrolidine derivatives from 5-bromo-1,2-oxazin-4-ones

Diastereoselective electrophilic bromination of 3,6-dihydro-2H-1,2-oxazines syn-1 and anti-1 led to 5-bromo-1,2-oxazin-4-ones 2a and 3a, respectively. Reduction furnished 1,2-oxazin-4-ones 4 and 6 which could be transformed into enantiopure amino and imin