53779-89-8

Basic information

• Product Name: azetidin-1-amine
• Synonyms: 1-Azetidinamine
• CAS NO: 53779-89-8
• Molecular Formula: C₃H₈N₂
• Molecular Weight: 72.109
• Mol File: 53779-89-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 82.6°C at 760 mmHg
• Flash Point: 14.7°C
• Density: 1.035g/cm³
• Vapor Pressure: 78mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: azetidin-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: azetidin-1-amine(53779-89-8)
• EPA Substance Registry System: azetidin-1-amine(53779-89-8)

Safety Data

• Hazardous Substances Data: 53779-89-8(Hazardous Substances Data)

Relevant articles and documents

N-Amino-1,8-Naphthalimide is a Regenerated Protecting Group for Selective Synthesis of Mono-N-Substituted Hydrazines and Hydrazides

A new route to synthesis of various mono-N-substituted hydrazines and hydrazides by involving in a new C?N bond formation by using N-amino-1,8-naphthalimide as a regenerated precursor was invented. Aniline and phenylhydrazines are reproduced upon reacting these individually with 1,8-naphthalic anhydride followed by hydrazinolysis. The practicality and simplicity of this C?N dihalo alkanes; developed a synthon for bond formation protocol was exemplified to various hydrazines and hydrazides. N-amino-1,8-naphthalimide is suitable synthon for transformation for selective formation of mono-substituted hydrazine and hydrazide derivatives. Those are selective mono-amidation of hydrazine with acid halides; mono-N-substituted hydrazones from aldehydes; synthesis of N-aminoazacycloalkanes from acetohydrazide scaffold and inserted to hydroxy derivatives; distinct synthesis of N,N-dibenzylhydrazines and N-benzylhydrazines from benzyl halides; synthesis of N-amino-amino acids from α-halo esters. Ecofriendly reagent N-amino-1,8-naphthalimide was regenerated with good yields by the hydrazinolysis in all procedures.