5378-41-6 Usage
Uses
Used in Pharmaceutical Industry:
2-Hydroxy-5-sulfamoylbenzoic acid is used as a diuretic medication for the treatment of fluid retention and swelling caused by congestive heart failure, liver disease, or kidney disease. It functions by promoting the production of urine and eliminating excess water and salt from the body, thereby alleviating the symptoms and complications related to these conditions.
Used in Congestive Heart Failure Treatment:
In the context of congestive heart failure, 2-hydroxy-5-sulfamoylbenzoic acid is used as a therapeutic agent to reduce the workload on the heart by decreasing the volume of fluid in the body. This helps in improving the heart's pumping efficiency and overall cardiovascular function.
Used in Liver Disease Management:
For patients suffering from liver disease, 2-hydroxy-5-sulfamoylbenzoic acid is utilized as a supportive treatment to manage the fluid buildup and swelling that can accompany liver dysfunction. By increasing urine output and reducing excess fluid, it helps in mitigating the discomfort and complications associated with liver-related edema.
Used in Kidney Disease Therapy:
In cases of kidney disease, 2-hydroxy-5-sulfamoylbenzoic acid is employed as a diuretic to assist the kidneys in eliminating excess water and salt from the body. This can help in managing the symptoms of kidney disease and supporting the overall health of the renal system.
Overall, 2-hydroxy-5-sulfamoylbenzoic acid, or Furosemide, plays a crucial role in the medical field as a diuretic agent, providing relief and management for patients dealing with fluid retention and swelling due to various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 5378-41-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,7 and 8 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 5378-41:
(6*5)+(5*3)+(4*7)+(3*8)+(2*4)+(1*1)=106
106 % 10 = 6
So 5378-41-6 is a valid CAS Registry Number.
5378-41-6Relevant academic research and scientific papers
SODIUM BOROHYDRIDE REDUCTION OF AROMATIC SULFONYL AZIDES IN THE PRESENCE OR ABSENCE OF TELLURIUM
Obafemi, Craig. A.,Onigbinde, Adebayo O.
, p. 75 - 81 (2007/10/02)
Some aromatic sulfonyl azides have been reduced, in various solvents, with sodium borohydride, in the presence or absence of Te element to the corresponding sulfonamides.Other functionals groups like the imino group may also be reduced.
Treatment of chronic inflammatory joint disease with arylsulfonamides
-
, (2008/06/13)
A method of treating chronic inflammatory joint disease with arylsulfonamides of the formula: wherein R1 and R2 are selected from hydrogen, lower alkyl, lower alkenyl, cycloalkyl, phenyl, loweralkylphenyl, 2 or 3 pyrrolidinyl, 2 or 3-(N-loweralkylpyrrolidinyl, or R1 and R2 taken together may form pyrrolidinyl or piperidinyl heterocyclic amino radicals and Z is an aryl group selected from substituted or unsubstituted tetrazole, 1,3,4-thiadiazole, 1,2,4-triazole, benzothiazole, benzimidazole, imidazole, pyridyl, 4,6-dimethyl pyrimidine, benzene or naphthalene is disclosed.
