53790-08-2

Basic information

• Product Name: N-(2-hydroxyethyl)-4-(trifluoromethyl)benzamide
• Synonyms: N-(2-hydroxyethyl)-4-(trifluoromethyl)benzamide
• CAS NO: 53790-08-2
• Molecular Weight: 233.19
• Mol File: 53790-08-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(2-hydroxyethyl)-4-(trifluoromethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-hydroxyethyl)-4-(trifluoromethyl)benzamide(53790-08-2)
• EPA Substance Registry System: N-(2-hydroxyethyl)-4-(trifluoromethyl)benzamide(53790-08-2)

Safety Data

• Hazardous Substances Data: 53790-08-2(Hazardous Substances Data)

Upstream product

• 329-15-7 4-trifluoromethyl-phenyl acetyl chloride 
• 141-43-5 ethanolamine 
• 455-24-3 4-trifluoromethylbenzoic acid 
• 2967-66-0 methyl 4-(trifluoromethyl)benzoate 

Downstream Products

• 286367-11-1 2-(4-(trifluoromethyl)phenyl)-4,5-dihydrooxazole 
• 359803-67-1 4-(trifluoromethyl)benzoic acid butyl ester 

Relevant articles and documents

A Mild and Regioselective Route to Functionalized Quinazolines

A Rh-catalyzed ortho-amidation cyclocondensation sequence gave a range of 4-aminoquinazolines in high yield. The method features a remarkably mild C(sp2)-H activation step and can be exploited to rapidly access compounds with established biological activity.

Organobase-catalyzed amidation of esters with amino alcohols

A base-mediated procedure for the amidation of unactivated esters with amino alcohols is reported. Optimization and exemplification of the catalytic process are described, furnishing products in 40-100% isolated yield.