5381-30-6

Usage

Uses

Used in Pharmaceutical Industry:
(1-benzothiophen-3-ylmethylidene)propanedinitrile is used as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structure and reactivity make it a valuable tool for organic chemists in the development of new drugs with potential biological activity.
Used in Agricultural Industry:
In the agricultural sector, (1-benzothiophen-3-ylmethylidene)propanedinitrile serves as a precursor for the production of agrochemicals. Its chemical properties allow for the creation of compounds that can be used in pest control and crop protection, contributing to more effective and sustainable agricultural practices.
Used in Organic Chemistry Research:
(1-benzothiophen-3-ylmethylidene)propanedinitrile is also utilized in the field of organic chemistry and chemical research. Its distinctive structure and chemical properties make it an interesting subject for scientists exploring new reactions, mechanisms, and the development of innovative synthetic pathways.

Upstream product

• 5381-20-4 benzothiophene-3-carboxaldehyde 
• 109-77-3 malononitrile 

Relevant academic research and scientific papers

Synthesis and anticholinesterase activity of novel non-hepatotoxic naphthyridine-11-amine derivatives

Abstract: In the present study, 14 novel naphthyridine-11-amine derivatives were synthesized and their inhibitory effects on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) were evaluated. 12-(4-Fluorophenyl)-1,2,3,4,7,8,9,10-octahydrodibenz

Molecular modeling of drug-pathophysiological Mtb protein targets: Synthesis of some 2-thioxo-1, 3-thiazolidin-4-one derivatives as anti-tubercular agents

Twenty novel 2-thioxo-1, 3-thiazolidin-4-one derivatives (5a-5t) were synthesized and evaluated for their antitubercular activity. The structure of the compounds was confirmed by IR, NMR and Mass Spectroscopy methods. In addition, single-crystal X-ray diffraction was performed for compound 5a. All the synthesized compounds were screened for their in-vitro antimycobacterial activity against MTB (H37RV, ATCC No: 27294) by Alamar Blue assay method. Compounds 5r, 5k, 5t displayed most potent in-vitro activity with MICs of 0.05, 0.1, 0.2 μg/ml concentrations respectively which are comparatively potent than the standards. Molecular docking and dynamics simulations were performed to find out the plausible mechanism of the titled compounds.