5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide is a metabolite of phenytoin, an anticonvulsant medication, produced in the body through the glucuronidation process. This process involves the attachment of a glucuronic acid molecule to the hydantoin ring structure, resulting in the formation of 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide. It is then excreted in the urine and plays a crucial role in monitoring the levels of phenytoin in patients to prevent drug toxicity and adverse effects.
53819-79-7
Post Buying Request-
-
Basic information
- Product Name: 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide
- Synonyms: 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide
- CAS NO:53819-79-7
- Molecular Formula: C21H20 N2 O9
- Molecular Weight: 444.39
- EINECS: N/A
- Product Categories: N/A
- Mol File: 53819-79-7.mol
-
Chemical Properties
- Melting Point: N/A
- Boiling Point: °Cat760mmHg
- Flash Point: °C
- Appearance: /
- Density: 1.579g/cm3
- Refractive Index: 1.67
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide(CAS DataBase Reference)
- NIST Chemistry Reference: 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide(53819-79-7)
- EPA Substance Registry System: 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide(53819-79-7)
-
Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 53819-79-7(Hazardous Substances Data)
53819-79-7 Suppliers
Recommended suppliers
53819-79-7 Usage
Uses
Used in Medical Applications:5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide is used as a biomarker for monitoring the levels of phenytoin in patients taking the medication. High levels of this metabolite may indicate drug toxicity, which can lead to adverse effects. By understanding the metabolic pathways and levels of 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide, healthcare professionals can manage phenytoin therapy more effectively and prevent potential toxic effects.
Used in Drug Monitoring and Management:
In the pharmaceutical industry, 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide is used as a critical parameter for assessing the efficacy and safety of phenytoin therapy. Monitoring the levels of this metabolite helps in adjusting the dosage and frequency of the medication, ensuring optimal therapeutic outcomes while minimizing the risk of drug toxicity.
Used in Research and Development:
5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide is utilized in research studies to investigate the metabolic pathways of phenytoin and its potential interactions with other drugs or substances. This knowledge aids in the development of new anticonvulsant medications with improved safety profiles and reduced side effects.
Used in Toxicology Studies:
In toxicology, 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide is employed as a biomarker to assess the potential toxic effects of phenytoin and other related compounds. Understanding the relationship between the levels of this metabolite and the occurrence of adverse effects can help in the identification of safer therapeutic alternatives.
Used in Quality Control and Compliance:
In the pharmaceutical manufacturing industry, 5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide is used as a quality control parameter to ensure the safety and efficacy of phenytoin-containing products. Regular testing and monitoring of this metabolite in pharmaceutical formulations help in maintaining compliance with regulatory standards and protecting patient health.
Check Digit Verification of cas no
The CAS Registry Mumber 53819-79-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,8,1 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.Calculate Digit Verification of CAS Registry Number 53819-79:
(7*5)+(6*3)+(5*8)+(4*1)+(3*9)+(2*7)+(1*9)=147
147 % 10 = 7
So 53819-79-7 is a valid CAS Registry Number.
InChI:InChI=1/C21H20N2O9/c24-13-14(25)16(17(27)28)32-18(15(13)26)31-12-8-6-11(7-9-12)21(10-4-2-1-3-5-10)19(29)22-20(30)23-21/h1-9,13-16,18,24-26H,(H,27,28)(H2,22,23,29,30)/t13-,14-,15+,16-,18?,21?/m0/s1
53819-79-7Upstream product
53819-79-7Downstream Products
Post a RFQ
1
What can I do for you?
Get Best Price
Get Best Price for 53819-79-7
5-phenyl-5-(4-hydroxyphenyl)hydantoin glucuronide
