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53823-08-8

Cascaroside A, a chemical compound found in certain plants such as the bark of Rhamnus purshiana (Cascara Sagrada), is an anthraquinone glycoside. It is a vital component in traditional medicine, known for its potent laxative effects. The mechanism of action of CASCAROSIDEA involves stimulating the muscles in the colon, which promotes regular bowel movements. Due to potential issues associated with overdosage and long-term use, its usage is regulated, and it is primarily used in the formulation of regulated over-the-counter drugs.

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  • (10S)-1-hydroxy-3-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-10H-anthracen-9-one

    Cas No: 53823-08-8

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  • 53823-08-8 Structure

  • Basic information

    1. Product Name: CASCAROSIDEA
    2. Synonyms: CASCAROSIDEA;10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)-9(10H)-anthracenone;10-β-D-Glucopyranosyl-8-(β-D-glucopyranosyloxy)-1-hydroxy-3-(hydroxymethyl)anthracen-9(10H)-one;Aloin 8-O-β-D-glucopyranoside
    3. CAS NO:53823-08-8
    4. Molecular Formula: C27H32O14
    5. Molecular Weight: 580.53458
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 53823-08-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 948.1 °C at 760 mmHg
    3. Flash Point: 315.2 °C
    4. Appearance: /
    5. Density: 1.694 g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.726
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 7.32±0.40(Predicted)
    11. CAS DataBase Reference: CASCAROSIDEA(CAS DataBase Reference)
    12. NIST Chemistry Reference: CASCAROSIDEA(53823-08-8)
    13. EPA Substance Registry System: CASCAROSIDEA(53823-08-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 53823-08-8(Hazardous Substances Data)

53823-08-8 Usage

Uses

Used in Pharmaceutical Industry:
CASCAROSIDEA is used as a laxative agent for promoting regular bowel movements. Its traditional use in natural form has been regulated due to concerns over overdosage and long-term use, leading to its incorporation into over-the-counter drugs.
Used in Traditional Medicine:
CASCAROSIDEA is used as a natural remedy for constipation, leveraging its potent laxative effects to stimulate the muscles in the colon and facilitate regular bowel movements. However, its use is carefully monitored to prevent potential health risks associated with excessive consumption or prolonged use.

Check Digit Verification of cas no

The CAS Registry Mumber 53823-08-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,8,2 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 53823-08:
(7*5)+(6*3)+(5*8)+(4*2)+(3*3)+(2*0)+(1*8)=118
118 % 10 = 8
So 53823-08-8 is a valid CAS Registry Number.
InChI:InChI=1/C27H32O14/c28-6-9-4-11-16(26-24(37)22(35)19(32)14(7-29)39-26)10-2-1-3-13(18(10)21(34)17(11)12(31)5-9)40-27-25(38)23(36)20(33)15(8-30)41-27/h1-5,14-16,19-20,22-33,35-38H,6-8H2/t14-,15-,16+,19-,20-,22+,23+,24-,25-,26+,27-/m1/s1

53823-08-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (10S)-1-hydroxy-3-(hydroxymethyl)-10-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-10H-anthracen-9-one

1.2 Other means of identification

Product number -
Other names UNII-AI50I7OZY7

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53823-08-8 SDS

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