53843-95-1

Usage

Uses

Used in Agricultural Industry:
(S)-benzyl 1-bromopropan-2-ylcarbamate is used as an acaricide for controlling pests such as mites and ticks. It is effective in managing these pests by disrupting their nervous system, causing paralysis and death, thereby protecting crops from damage.
It is important to handle (S)-benzyl 1-bromopropan-2-ylcarbamate with care, as it can cause irritation to the skin, eyes, and respiratory system if not properly managed.

Upstream product

• 6429-44-3 (S)-(-)-N-(benzyloxycarbonyl)alaninol 
• 83197-70-0 (S)-2-(benzyloxycarbonylamino)propyl methanesulfonate 

Relevant academic research and scientific papers

HETEROCYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS COMPRISING THESE COMPOUNDS, AND THE USE THEREOF

Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, T and Y have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example for the treatment of the metabolic syndrome, insulin resistance, obesity and diabetes.

Optically active N- and C-terminal building blocks for the synthesis of peptidyl olefin peptidomimetics

Peptidyl olefin peptidomimetics serve as biologically active compounds or as intermediates for other peptidyl isosteres. The N-terminal side of the C=C bond could be easily prepared in an optically pure form from α-amino acids. Synthesis of C-terminal building blocks in an optically pure form is more challenging. We developed a chemoenzymatic stereoselective approach to such optically active C-terminal building blocks to be assembled into peptidyl olefins by a variety of reactions. They include an electrophilic aldehyde and nucleophilic sulfone, phosphonium salt, phosphonate, and diselenide. Key enzymatic hydrolysis of prochiral diesters to the corresponding hydroxy esters introduces optical activity. The sequence of the subsequent chemical reactions, either protection- hydrolysis-functionalization or functionalization-hydrolysis- protection, determines the absolute stereochemistry of the final building blocks.

Stereoselective synthesis of 1,3-substituted tetrahydroisoquinolines through palladium-catalyzed three-component reaction

Chiral 1,3-substituted 1,2,3,4-tetrahydroisoquinolines have been synthesized in acceptable yield and diastereoselectivity through a three component reaction, starting from aromatic halides, enantiopure bromoalkyl derivatives and methyl acrylate, under pal