53857-09-3

Basic information

• Product Name: 1,5-Hexanedione, 1,3-diphenyl-
• CAS NO: 53857-09-3
• Molecular Formula: C18H18O2
• Molecular Weight: 266.34
• Mol File: 53857-09-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,5-Hexanedione, 1,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Hexanedione, 1,3-diphenyl-(53857-09-3)
• EPA Substance Registry System: 1,5-Hexanedione, 1,3-diphenyl-(53857-09-3)

Safety Data

• Hazardous Substances Data: 53857-09-3(Hazardous Substances Data)

Upstream product

• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 94-41-7 benzalacetophenone 
• 100636-60-0 (Z)-1,3-Diphenyl-5-trimethylsilanyloxy-hex-4-en-1-one 
• 1408003-22-4 (Z)-6-acetoxy-4,6-diphenyl-5-hexen-2-one 
• 21136-48-1 1,3-diphenylhex-5-en-1-one 
• 1170695-27-8 C₁₃H₂₂OSi₂ 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 614-47-1 1,3-diphenyl-propen-3-one 
• 13735-81-4 1-styrenyloxytrimethylsilane 

Downstream Products

• 1433845-41-0 C₁₈H₁₈O₂ 
• 1228812-18-7 (S)-1,3-diphenylhexane-1,5-dione 
• 10346-08-4 3,5-diphenylcyclohex-2-en-1-one 
• 1912-16-9 2-methyl-4,6-diphenyl-pyridine 

Relevant articles and documents

Route to Highly Substituted Pyridines

Pyridine rings are common structural motifs found in a number of biologically active compounds, including some top-selling pharmaceuticals. We have developed a new approach to access substituted pyridines. The method aims to provide a reliable synthesis of a diverse range of substituted pyridines through a three-step procedure. Readily available enones are first converted into 1,5-dicarbonyls through a two-step Hosomi-Sakurai allylation/oxidative cleavage sequence, which is followed by subsequent cyclization to the corresponding pyridine using hydroxylamine hydrochloride. A variety of substituted pyridines have been synthesized using this method.

Synthesis of N,N-Bis(nonaflyl) squaric acid diamide and its application to organic reactions

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Organocatalytic kinetic resolution via intramolecular aldol reactions: Enantioselective synthesis of both enantiomers of chiral cyclohexenones

Kinetic resolution of 6-aryl-2,6-hexanediones was achieved with chiral secondary amine catalyzed intramolecular aldolization. The current kinetic resolution protocol enables the synthesis of both enantiomers of cyclohexenones with moderate to good enantioselectivity. The Royal Society of Chemistry 2010.