53872-16-5

Upstream product

• 53872-40-5 dimethyl ((4-methoxybenzoyl)amino)propanedioate 
• 6773-29-1 dimethyl diazomalonate 
• 874-90-8 4-methoxybenzonitrile 

Downstream Products

• 154405-98-8 methyl 2-(4-methoxyphenyl)-1,3-oxazole-4-carboxylate 
• 53872-24-5 2-(4-methoxy-phenyl)-5-(N-methyl-anilino)-oxazole-4-carboxylic acid methyl ester 
• 51974-31-3 5-methoxy-2-(4-methoxy-phenyl)-oxazole-4-carboxylic acid N-methyl-anilide 
• 556104-39-3 (4S,5R)-5-(4-benzyloxy-3-hydroxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester 
• 821006-09-1 (4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester 
• 556104-38-2 (4R,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Rhodium-catalyzed heterocycloaddition route to 1,3-oxazoles as building blocks in natural products synthesis

Rhodium(II) acetate serves as a catalyst for the heterocycloaddition reaction of diazodicarbonyl compounds with nitriles to give functionalized 1,3-oxazole derivatives in a simple one-step procedure. In particular, dimethyl diazomalonate undergoes this re

Functionalized Oxazoles from Rhodium-Catalyzed Reaction of Dimethyl Diazomalonate with Nitriles

Rhodium(II) acetate catalyzes the reaction of dimethyl diazomalonate with nitriles to give 4-carbomethoxy-5-methoxy-1,3-oxazoles.Oxazole formation exceeds cyclopropane formation even in cases of conjugated and non-conjugated unsaturated nitriles.