53875-03-9Relevant academic research and scientific papers
SAcid- and Base-catalysed Reactions of 4β,5β- and 4α,5α-Epoxyandrostane-3,17,19-trione
Mastalerz, Harold,Morand, Peter
, p. 2611 - 2616 (2007/10/02)
The acid- and base-catalysed reactions of 4β,5β- and 4α,5α-epoxyandrostane-3,17,19-triones (2) and (7) have been examined to see if epoxide opening in these compounds would result in elimination of the C-10 substituent and the subsequent formation of estrone (25).However, the products obtained indicated the epoxide solvolysis or rearrangement concominant with epoxide opening is the predominant mode of reaction under the conditions examined.
