53877-76-2Relevant academic research and scientific papers
FUNCTIONALIZED CHLOROENAMINES IN AMINOCYCLOPROPANE SYNTHESIS - XV. SYNTHESIS OF CONFORMATIONALLY RIGID ANALOGUES OF -4'-CARBOXAMIDE - A COMMON PHARMACOPHORIC GROUP
Schlag, Wolf-Ruediger,Vilsmaier, Elmar,Maas, Gerhard
, p. 3123 - 3138 (2007/10/02)
6-Piperidino-3-azabicyclohexane-6-carboxamide diastereomers 5 and 7 represent conformationally rigid analogues of the pharmacophoric group 1.Compounds 5 and 7 were synthesized with high stereoselectivity via chloroenamines 12a and 13b, respectively
