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Cyclooctane-1,4-diol is an organic compound with the molecular formula C8H14O2. It is a cyclic alkane with two hydroxyl groups attached to the 1st and 4th carbon atoms, forming a diol. This white crystalline solid is known for its unique ring structure and is used in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Cyclooctane-1,4-diol is also a key intermediate in the production of certain polymers and has potential applications in the development of new materials. Its chemical properties and reactivity make it an important compound in the field of organic chemistry.

5388-47-6

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5388-47-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5388-47-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,3,8 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5388-47:
(6*5)+(5*3)+(4*8)+(3*8)+(2*4)+(1*7)=116
116 % 10 = 6
So 5388-47-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H16O2/c9-7-3-1-2-4-8(10)6-5-7/h7-10H,1-6H2

5388-47-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name cyclooctane-1,4-diol

1.2 Other means of identification

Product number -
Other names EINECS 226-379-4

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5388-47-6 SDS

5388-47-6Relevant academic research and scientific papers

A Cu-Doped ZIF-8 metal organic framework as a heterogeneous solid catalyst for aerobic oxidation of benzylic hydrocarbons

Nagarjun, Nagarathinam,Dhakshinamoorthy, Amarajothi

supporting information, p. 18702 - 18712 (2019/12/09)

Mixed-metal metal organic frameworks have received considerable attention in recent years and it has been shown that the activity of the parent metal organic framework (MOF) is often enhanced upon doping with external metal ions within the framework. In this context, Cu2+ ions with different loadings were incorporated within the ZIF-8 framework to obtain a series of Cu-doped ZIF-8 materials and their activity was examined in the aerobic oxidation of hydrocarbons. The as-synthesized Cu-doped solids were characterized by powder X-ray diffraction (XRD), ultraviolet diffuse reflectance spectroscopy (UV-DRS), scanning electron microscopy (SEM), Fourier Transform infrared (FT-IR), electron paramagnetic resonance (EPR) and inductively coupled plasma (ICP) analysis. The experimental results revealed that the activity of Cu-doped ZIF-8 is much higher than that of the parent ZIF-8 in all the tested substrates at 120 °C. Furthermore, the activity of the Cu-doped ZIF-8 with the highest Cu loading was eight fold higher than that of the parent ZIF-8 in the aerobic oxidation of cyclooctane (1) at 120 °C with more than 80% selectivity to the corresponding cyclooctanol/cyclooctanone (ol/one) mixture. Cu-doped ZIF-8 was reused two times with no significant drop in its activity under identical conditions. Furthermore, comparison of the two times reused solid with that of the fresh solid by powder XRD and SEM analysis revealed identical structural integrity and morphology, respectively during the oxidation reactions.

Selective oxidation of saturated hydrocarbons using Au-Pd alloy nanoparticles supported on metal-organic frameworks

Long, Jilan,Liu, Hongli,Wu, Shijian,Liao, Shijun,Li, Yingwei

, p. 647 - 654 (2013/05/21)

Gold (Au) and palladium (Pd) nanoparticles dispersed on a zeolite-type metal-organic framework (i.e., MIL-101) were prepared via a simple colloidal method. The catalysts were characterized by powder X-ray diffraction, N 2 physical adsorption, atomic absorption spectroscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray photoelectron spectroscopy. Au and Pd were mostly in the form of bimetallic alloys on the MIL-101 support. The Au-Pd/MIL-101 was active and selective in the oxidation of a variety of saturated (including primary, secondary, and tertiary) C-H bonds with molecular oxygen. For the liquid-phase oxidation of cyclohexane, cyclohexane conversion exceeding 40% was achieved (TOF: 19 000 h-1) with >80% selectivity to cyclohexanone and cyclohexanol under mild solvent-free conditions. Moreover, the Au-Pd alloy catalyst exhibited higher reactivity than their pure metal counterparts and an Au + Pd physical mixture. The high activity and selectivity of Au-Pd/MIL-101 in cyclohexane aerobic oxidation may be correlated to the synergistic alloying effect of bimetallic Au-Pd nanoparticles.

Molecular addition compounds. 14. Convenient preparations of representative dialkylborane reagents using the new, highly reactive N- ethyl-N-isopropylaniline-borane reagent (BACH-EI(TM))

Brown, Herbert C.,Kanth, Josyula V. B.,Zaidlewicz, Marek

, p. 5991 - 6000 (2007/10/03)

Convenient procedures for the preparation of representative dialkylborane reagents, diisopinocampheylborane, [1S]-2-diisocaranylborane, 9-borabicyclo[3,3,1]nonane, dicyclohexylborane and disiamylborane, using the new, highly reactive N-ethyl-N-isopropylaniline-borane reagent (BACH-EI(TM)) in dioxane and tetrahydrofuran are described.

Catalytic Reactions of Metalloporphyrins. 3. Catalytic Modification of Hydroboration-Oxidation of Olefin with Rhodium(III) Porphyrin as Catalyst

Aoyama, Yasuhiro,Tanaka, Yasutaka,Fujisawa, Takeshi,Watanabe, Takamichi,Toi, Hiroo,Ogoshi, Hisanobu

, p. 2555 - 2559 (2007/10/02)

(Octaethylporphyrinato)- or (tetraphenylporphyrinato)rhodium(III) chloride catalyzes the anti-Marcovnikov "hydration" of olefin with NaBH4 and O2 in THF. 1,5-Cyclooctadiene gives rise to cyclooctanol and 1,5-cyclooctanediol (in a ratio of approximately 1:2), and acetylenes are converted directly to alcohols under similar conditions.The initial step in the catalytic reaction of olefin is the hydride and borane transfers from BH4- respectively to RhIII porphyrin and olefin to give hydridorhodium (RhH) porphyrin and alkylborane.The RhH species undergoesoxidation with O2 back to RhIII with concomitant oxidation of alkylborane with retention of configuration.This coupled oxidation of alkylborane is in competition with its nonstereospecific autooxidation without assistance of Rh-H.The present system provides a catalytic modification of hydroboration-oxidation of olefin in the presence of oxygen, as illustrated by the one-pot conversion of 1-methylcyclohexene to (E)-2-methylcyclohexanol with 100 percent regioselectivity and up to 97 percent stereoselectivity.

Vinyl Epoxide Hydrolysis Reactions

Ross, Angela M.,Pohl, Terese M.,Piazza, Kathryn,Thomas, Michael,Fox, Bonnie,Whalen, Dale L.

, p. 1658 - 1665 (2007/10/02)

The rates of hydrolysis of cyclopentadiene oxide (3), cyclohexadiene oxide (4), cycloheptadiene oxide (5), cyclooctadiene oxide (6), butadiene oxide (7), and styrene oxide (8) have been determined as a function of pH.Each epoxide exhibited acid-catalyzed hydrolysis at low pH, and 3-5 showed significant rates for "spontaneous" reaction with solvent at intermediate pH values.The hydrolyses of several of the vinyl epoxides (4 and 5) showed kinetic terms in HO- at pH > ca. 13.Specific chloride effects attributed to nucleophilic addition of Cl- to neutral epoxide were observed for those compounds (3, 4, and 8) hydrolyzed in KCl solutions.From kinetic and product studies, mechanisms for hydrolyses of the vinyl epoxides are postulated.Acid-catalyzed hydrolyses of 3, 4, 5, and 6 were found to be A-1 in nature, proceeding via intermediate allyl cations.Product distributions depended on the structure of the cation.Mechanisms and product distributions for the spontaneous hydrolyses of vinyl epoxides were found to be variable, and dependent on the structure of the epoxide.

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