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Usage

Uses

Used in Flavor and Fragrance Industry:
2-methoxy-4-prop-2-enyl-phenol is used as a flavoring agent for its aromatic properties, adding a unique taste and scent to various food and beverage products. Its characteristic flavor makes it a popular choice in the creation of spices, condiments, and other consumable items.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-methoxy-4-prop-2-enyl-phenol is utilized as an active ingredient in the development of drugs targeting various health conditions. Its chemical structure allows for potential interactions with biological systems, making it a valuable compound for medicinal applications.
Used in Cosmetics Industry:
2-methoxy-4-prop-2-enyl-phenol is also employed in the cosmetics industry, where it serves as a key component in the formulation of various personal care products. Its aromatic qualities and potential therapeutic properties contribute to the development of fragrances, skincare, and hair care products.
Used in Research and Development:
Due to its unique chemical structure and properties, 2-methoxy-4-prop-2-enyl-phenol is a valuable compound for research and development purposes. It can be used in the synthesis of new compounds, the study of chemical reactions, and the exploration of potential applications in various fields, including material science and biotechnology.

InChI:InChI=1/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3

Upstream product

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Relevant academic research and scientific papers

Anti-proliferative, apoptotic induction, and anti-migration effects of hemi-synthetic 1’S-1’-acetoxychavicol acetate analogs on MDA-MB-231 breast cancer cells

Nine analogs of 1′S-1′-acetoxychavicol acetate (ACA) were hemi-synthesized and evaluated for their anticancer activities against seven human cancer cell lines. The aim of this study was to investigate the anti-proliferative, apoptotic, and anti-migration effects of these compounds and to explore the plausible underlying mechanisms of action. We found that ACA and all nine analogs were non toxic to human mammary epithelial cells (HMECs) used as normal control cells, and only ACA, 1′-acetoxyeugenol acetate (AEA), and 1′-acetoxy-3,5-dimethoxychavicol acetate (AMCA) inhibited the growth of MDA-MB-231 breast cancer cells with a half-maximal inhibitory concentration (IC50) value of 30.0 μM based on 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay results, and were selected for further investigation. DNA fragmentation assays showed that these three compounds markedly induced apoptosis of MDA-MB-231 cells. Western blot analysis revealed increased expression levels of cleaved PARP, p53, and Bax, while decreased expression levels of Bcl-2 and Bcl-xL were seen after treatment, indicating that apoptosis was induced via the mitochondrial pathway. Moreover, ACA, AEA, and AMCA effectively inhibited the migration of MDA-MB-231 cells. They also downregulated the expression levels of pFAK/FAK and pAkt/Akt via the integrin β1-mediated signaling pathway. Collectively, ACA and its hemi-synthetic analogs, AEA and AMCA are seen as potential anticancer agents following their abilities to suppress growth, induce apoptosis, and inhibit migration of breast cancer cells.