53954-32-8

Upstream product

• 75154-93-7 (6Z)-9,10-secocholesta-5⁽¹⁰⁾,6,8-trien-1-one 
• 1193-55-1 2-methylcyclohexane-1,3-dione 
• 67619-70-9 2-methyl-3-iodocyclohex-2-en-1-ol 
• 74398-26-8 (6R)-9,10-secocholesta-5⁽¹⁰⁾,6,7-triene-1-one 
• 74398-25-7 de-A,B-8α-ethynyl-8β-cholestanol benzoate 
• 67619-75-4 de-A,B-8α-ethynyl-8β-cholestanol 
• 93490-17-6 (8E)-8-bromomethylene-de-A,B-cholestane 
• 122700-33-8 3-(tert-Butyl-dimethyl-silanyloxy)-8-trimethylsilanyl-oct-1-en-7-yne 
• 29329-03-1 5-hexynal 
• 168132-43-2 tert-Butyl-{(S)-3-[2-[(1R,3aS,7aR)-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-2-methylene-cyclohexyloxy}-dimethyl-silane 
• 75154-97-1 (1S,6Z)-1-hydroxy-9,10-secocholesta-5⁽¹⁰⁾,6,8-triene 
• 67670-78-4 (1S,6R)-1-hydroxy-9,10-secocholesta-5⁽¹⁰⁾,6,7-triene 
• 75154-94-8 (6Z)-9,10-secocholesta-5⁽¹⁰⁾,6,8⁽¹⁴⁾-trien-1-one 
• 67619-71-0 1-tert-butyldimethylsiloxy-2-methyl-3-iodocyclohex-2-ene 

Downstream Products

• 75154-97-1 (1S,6Z)-1-hydroxy-9,10-secocholesta-5⁽¹⁰⁾,6,8-triene 

Relevant academic research and scientific papers

Alkenylzinc-Mediated Approach to the Vitamin D Skeleton. Application to the Synthesis of 6-Methyl Analogs of Vitamin and Previtamin D

Palladium-catalyzed cross-coupling of alkenylzinc reagents, bearing the C,D-ring/side chain portion, and (Z)-1-iodo-1,3-bis-exocyclic dienes (as A-ring precursors), provides a mild, convergent entry to the vitamin D skeleton, that is suitable for the synt

A mild palladium-catalysed convergent approach to the vitamin D skeleton

Palladium-catalysed cross-coupling of (Z)-1-iodo-1,3-bis-exocyclic dienes and alkenyl-zinc reagents bearing the C,D-ring/side chain portion provides a new efficient entry to the tricyclic system of vitamin D.

Studies on Vitamin D (Calciferol) and Its Analogues. 18. The Vinylallene Approach to the 1-Hydroxyvitamin D System. New Sigmatropic Reactions in the Vitamin D Series

The thermally induced -sigmatropic hydrogen shift of the diastereomeric vitamin D type vinylallenols 6a (1R,6R), 6b (1R,6S), 7a (1S,6S) and vinylallenols 5a (6R) and 5b (6S) were studied.The 1S,6S (7b) and 1R,6R(6a) alcohols afforded ca. 60percent yi