53963-40-9Relevant academic research and scientific papers
A Convenient Method for the Transformation of Allylstannanes to Alcohols, Ethers, Esters, and Amines
Takeda, Takeshi,Inoue, Tomoya,Fujiwara, Tooru
, p. 985 - 988 (2007/10/02)
Allylstannanes were easily oxidized with copper(II) bromide in the presence of water, alcohols, and sodium acetate to give the corresponding allylic alcohols, ethers, and acetates, respectively.The allylic amines were also obtained by the succesive treatm
Reaction of Acetals with Grignard Reagents
Ishikawa, Hiroshi,Mukaiyama, Teruaki,Ikeda, Shigeru
, p. 776 - 780 (2007/10/02)
The reaction of dialkyl acetals derived from α,β-unsaturated aldehydes with Grignard reagents using TiCl4 in THF afforded the cross coupling products, allyl ethers, in high yields.The TiCl4-promoted reaction of alkyl 2,4-dichlorophenyl acetals, synthesized from 3,4-dihydro-2H-pyran or ethyl vinyl ether and 2,4-dichlorophenol, with Grignard reagents in THF at low temperature afforded the corresponding unsymmetrical ethers in high yields.When alkyl 2,4-dichlorophenyl acetals, synthesized from aromatic aldehyde or vinyl ethers and 2,4-dichlorophenol, were treated with Grignard reagents in benzene or toluene at room temperature in the absence of TiCl4, the cross coupling reaction took place and the corresponding ethers were isolated in good yields.
