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1-Isopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, commonly known as nalidixic acid, is a synthetic quinolone antibiotic with broad-spectrum activity against both Gram-positive and Gram-negative bacteria. It functions by inhibiting bacterial DNA gyrase, which is essential for DNA replication and repair, thereby disrupting bacterial growth. Nalidixic acid is particularly useful in treating urinary tract infections, gastrointestinal infections, and certain respiratory infections. However, its use has been limited due to the emergence of bacterial resistance and the availability of newer quinolone antibiotics. Despite these challenges, nalidixic acid continues to be an important drug in regions where resistance to other antibiotics is less prevalent.

53977-47-2

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53977-47-2 Usage

Uses

Used in Pharmaceutical Industry:
1-Isopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is used as an antibacterial agent for the treatment of various infections caused by susceptible bacteria. Its broad-spectrum activity makes it effective against a wide range of bacterial species, including both Gram-positive and Gram-negative organisms.
Used in Urinary Tract Infections Treatment:
1-Isopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is used as a therapeutic agent for urinary tract infections, where it targets and eliminates the causative bacteria, reducing inflammation and alleviating symptoms.
Used in Gastrointestinal Infections Treatment:
1-Isopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is used as an antimicrobial agent for gastrointestinal infections, helping to control bacterial overgrowth and restore the balance of the gut microbiome.
Used in Respiratory Infections Treatment:
1-Isopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is used as a respiratory tract infection treatment, particularly for infections caused by susceptible bacterial strains, where it can help clear the infection and improve respiratory function.
Used in Regions with Limited Antibiotic Resistance:
1-Isopropyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid is used as a primary antibiotic in regions where resistance to other antibiotics is less common, providing an effective treatment option for bacterial infections in these areas.

Check Digit Verification of cas no

The CAS Registry Mumber 53977-47-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,3,9,7 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 53977-47:
(7*5)+(6*3)+(5*9)+(4*7)+(3*7)+(2*4)+(1*7)=162
162 % 10 = 2
So 53977-47-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H13NO3/c1-8(2)14-7-10(13(16)17)12(15)9-5-3-4-6-11(9)14/h3-8H,1-2H3,(H,16,17)/p-1

53977-47-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-ISOPROPYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXYLIC ACID

1.2 Other means of identification

Product number -
Other names 1-ISOPROPYL-4-OXO-1,4-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:53977-47-2 SDS

53977-47-2Upstream product

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