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Pneumocandin A0 is a potent lipopeptide antibiotic and a natural product derived from the fungus Glarea lozoyensis. It exhibits significant pharmaceutical interest due to its broad-spectrum antifungal activity against various fungal pathogens, such as Candida and Aspergillus species. Pneumocandin A0 targets the enzyme 1,3-beta-D-glucan synthase, inhibiting the synthesis of beta-glucan, a crucial component of the fungal cell wall. This disruption in cell wall formation results in the death of fungal cells, making Pneumocandin A0 a promising candidate for the development of antifungal drugs.

539823-80-8

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539823-80-8 Usage

Uses

Used in Pharmaceutical Industry:
Pneumocandin A0 is used as an antifungal agent for its potent activity against a wide range of fungal pathogens, including Candida and Aspergillus species. Its ability to inhibit the synthesis of beta-glucan by targeting the enzyme 1,3-beta-D-glucan synthase makes it an effective treatment for invasive fungal infections.
Used in Drug Development:
Pneumocandin A0 serves as the basis for the development of the antifungal drug caspofungin, which is used clinically for the treatment of invasive fungal infections. Its unique mechanism of action and broad-spectrum antifungal activity make it a valuable asset in the development of new antifungal drugs to combat drug-resistant fungal strains.

Check Digit Verification of cas no

The CAS Registry Mumber 539823-80-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,3,9,8,2 and 3 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 539823-80:
(8*5)+(7*3)+(6*9)+(5*8)+(4*2)+(3*3)+(2*8)+(1*0)=188
188 % 10 = 8
So 539823-80-8 is a valid CAS Registry Number.
InChI:InChI=1/C56H71N9O19/c1-4-5-6-19-83-34-17-13-29(14-18-34)40-22-35(63-84-40)28-7-9-31(10-8-28)49(75)58-36-21-39(70)52(78)62-54(80)45-46(72)26(2)24-65(45)56(82)43(38(69)23-41(57)71)60-53(79)44(48(74)47(73)30-11-15-32(67)16-12-30)61-51(77)37-20-33(68)25-64(37)55(81)42(27(3)66)59-50(36)76/h7-18,22,26-27,33,36-39,42-48,52,66-70,72-74,78H,4-6,19-21,23-25H2,1-3H3,(H2,57,71)(H,58,75)(H,59,76)(H,60,79)(H,61,77)(H,62,80)

539823-80-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 539823-80-8

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:539823-80-8 SDS

539823-80-8Upstream product

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