539836-15-2

Upstream product

• 539836-14-1 Acetic acid (2R,3S,4R,5R,6S)-5-benzenesulfonylamino-6-[(2R,3S,4R,5R,6R)-5-benzenesulfonylamino-4-benzyloxy-2-benzyloxymethyl-6-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran-3-yloxy]-4-benzyloxy-2-benzyloxymethyl-tetrahydro-pyran-3-yl ester 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 187879-68-1 Acetic acid (2R,3S,4R,5R,6S)-5-benzenesulfonylamino-4-benzyloxy-6-((2R,3S,4R)-4-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyran-3-yloxy)-2-benzyloxymethyl-tetrahydro-pyran-3-yl ester 
• 539836-13-0 Acetic acid (2R,3S,4R,5R,6S)-5-benzenesulfonylamino-6-((2R,3S,4R,5R,6S)-5-benzenesulfonylamino-4-benzyloxy-2-benzyloxymethyl-6-hydroxy-tetrahydro-pyran-3-yloxy)-4-benzyloxy-2-benzyloxymethyl-tetrahydro-pyran-3-yl ester 

Downstream Products

• 539836-16-3 C₈₆H₉₈N₂O₁₉S₂Si 

Relevant academic research and scientific papers

Toward a prostate specific antigen-based prostate cancer diagnostic assay: Preparation of keyhole limpet hemocyanin-conjugated normal and transformed prostate specific antigen fragments

Prostate specific antigen (PSA) molecules secreted by cancerous and normal prostate cells differ in their N-linked glycan composition, while the peptide backbone appears to be conserved. Antibodies selectively recognizing such differentially glycosylated

A concise route to the core pentasaccharide of N-linked glycoproteins

A concise preparation of the common pentasaccharide core of the N-linked glycoproteins is described. The reducing end glycal is functionalized at the level of chitobiose, which is then β-mannosylated using Crich's direct coupling protocol. Deprotection of the branching mannose residue, and di-α-mannosylation complete the synthesis.