5399-41-7

Basic information

• Product Name: (3beta,5alpha)-3-hydroxy-4,4,14-trimethyl-7,11-dioxocholan-24-oic acid
• CAS NO: 5399-41-7
• Molecular Formula: C₂₇H₄₂O₅
• Molecular Weight: 446.6194
• Mol File: 5399-41-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 584.9°C at 760 mmHg
• Flash Point: 321.6°C
• Density: 1.124g/cm³
• Vapor Pressure: 4.08E-16mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: (3beta,5alpha)-3-hydroxy-4,4,14-trimethyl-7,11-dioxocholan-24-oic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (3beta,5alpha)-3-hydroxy-4,4,14-trimethyl-7,11-dioxocholan-24-oic acid(5399-41-7)
• EPA Substance Registry System: (3beta,5alpha)-3-hydroxy-4,4,14-trimethyl-7,11-dioxocholan-24-oic acid(5399-41-7)

Safety Data

• Hazardous Substances Data: 5399-41-7(Hazardous Substances Data)

Usage

Description

(3beta,5alpha)-3-hydroxy-4,4,14-trimethyl-7,11-dioxocholan-24-oic acid, also known as ursocholic acid, is a bile acid that is naturally present in the digestive system of mammals. It is a derivative of cholic acid and plays a vital role in the digestion and absorption of fats and fat-soluble vitamins. Ursocholic acid has been studied for its potential therapeutic effects in treating various liver and gastrointestinal disorders, including gallstones and liver diseases. It has also been investigated for its anti-inflammatory and immunomodulatory properties. Additionally, ursocholic acid has shown promise in the treatment of certain types of cancer and as a potential agent for the prevention of cholestasis. Its unique chemical structure and biological activities make it a subject of interest for further pharmacological and clinical research.

Uses

Used in Pharmaceutical Industry:
Ursocholic acid is used as a therapeutic agent for the treatment of various liver and gastrointestinal disorders, such as gallstones and liver diseases. Its application is based on its ability to improve bile flow and reduce the formation of gallstones, as well as its potential to alleviate liver inflammation and promote liver regeneration.
Used in Gastrointestinal Applications:
Ursocholic acid is used as a treatment for gastrointestinal disorders due to its role in the digestion and absorption of fats and fat-soluble vitamins. It helps in the proper functioning of the digestive system and can be particularly beneficial for individuals with malabsorption issues.
Used in Anti-inflammatory and Immunomodulatory Applications:
Ursocholic acid is used as an anti-inflammatory and immunomodulatory agent, owing to its potential to reduce inflammation and modulate the immune system. This makes it a promising candidate for the treatment of conditions characterized by chronic inflammation or immune system dysregulation.
Used in Cancer Treatment:
Ursocholic acid is used as a potential therapeutic agent in the treatment of certain types of cancer. Its application is based on its ability to target cancer cells and inhibit their growth, as well as its potential to enhance the efficacy of conventional chemotherapeutic drugs.
Used in Prevention of Cholestasis:
Ursocholic acid is used as a preventive agent for cholestasis, a condition characterized by the impairment of bile flow. Its application is based on its ability to improve bile secretion and reduce the risk of developing cholestasis.

Upstream product

• 39083-50-6 3β-hydroxy-7,11-dioxo-25,26,27-trinor-lanost-8-en-24-oic acid 

Downstream Products

• 67493-64-5 3β-acetoxy-7,11-dioxo-25,26,27-trinor-lanostan-24-oic acid