nootropic Anti-Alzheimer’s drug main ingredient of Neupramir derived from Piracetam but 8-30 times more potent
Thiomersal is an organomercury compound that is used as an antiseptic and antifungal agent It is used as a vaccine preservative. During cell culture, thiomersal is used to prevent overgrowth in fibroblast cells 1. It has been used to preserve Atovaquone 2.
ChEBI: An alkylmercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent.
Light cream-colored crystalline powder with a slight odor: pH (1% aqueous solution) 6.7. Slight odor.
Flash point data for Thimerosal are not available; however, Thimerosal is probably combustible.
Pharmaceutic aid (preservative).
Toxic by ingestion, inhalation.
Slightly beige powder
Thiomersal is INN and BAN.
Recrystallise this antibacterial from EtOH/Et2O. HIGHLY TOXIC. [Trikojus Nature 158 472 1940, Beilstein 10 III 213.]
Thiomersal is an organic mercury salt prepared by react-
ing ethylmercuric chloride (or ethylmercuric hydroxide)
with thiosalicylic acid. It is still used as a disinfectant
and a preservative agent, but less commonly than previ-
ously, especially in contact lens fluids, eyedrops, and
vaccines. The ethylmercuric moiety is the major aller-
genic determinant, sometimes associated with mercury
sensitivity. Thiomersal is an indicator of photosensitiv-
ity to piroxicam, through its thiosalicylic moiety.
Thimerosal is incompatible with strong oxidizing agents and strong bases. The oxidation of Thimerosal is greatly accelerated by traces of copper ions. Incompatible with acids, iodine, heavy metal salts and many alkaloids. Can be absorbed by rubber caps. . Stable in air, but not sunlight. May discolor on exposure to light. Dilute aqueous solutions are fairly stable to heat but sensitive to light. Solutions are less stable to heat when acidic than when alkaline. Solutions are most stable to light at pH 5 to 7. Solutions are unstable to heat but not to light in the presence of copper, iron or zinc ions but not in the presence of calcium or magnesium ions.
Air & Water Reactions