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54-91-1

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1,4-Bis-(3-bromo-1-oxopropyl)piperazine
Cas No: 54-91-1
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
1,1'-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one)
Cas No: 54-91-1
No Data 10 Milligram Amadis Chemical Co., Ltd. Contact Supplier
Pipobroman
Cas No: 54-91-1
No Data No Data No Data Chemwill Asia Co., Ltd. Contact Supplier
Pipobroman
Cas No: 54-91-1
No Data 1 Gram 1000 Gram/Week Shanghai BetterBioChem Co., Ltd. Contact Supplier
Pipobroman
Cas No: 54-91-1
No Data 1 Kilogram 100 Kilogram/Day HANGZHOU CLAP TECHNOLOGY CO,.LTD Contact Supplier
1-Propanone,1,1'-(1,4-piperazinediyl)bis[3-bromo-
Cas No: 54-91-1
No Data 1 Kilogram 1 Metric Ton/Month HANGZHOU YUNUO CHEMICAL CO.,LTD Contact Supplier
1,4-Bis-(3-bromo-1-oxopropyl)piperazine CAS NO.54-91-1
Cas No: 54-91-1
No Data No Data No Data Jilin haofei import and export trade Co.,Ltd Contact Supplier
1,1'-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one)
Cas No: 54-91-1
No Data No Data No Data Hunan chemfish Pharmaceutical co.,Ltd Contact Supplier
1,4-Bis-(3-bromo-1-oxopropyl)piperazine
Cas No: 54-91-1
No Data No Data No Data Antimex Chemical Limied Contact Supplier
1,4-Bis-(3-bromo-1-oxopropyl)piperazine cas 54-91-1
Cas No: 54-91-1
No Data No Data No Data Hangzhou Fandachem Co.,Ltd Contact Supplier

54-91-1 Usage

Originator

Vercyte ,Abbott ,US ,1966

Uses

diuretic, antihypertensive

Manufacturing Process

To a solution of 17.2 g (0.10 mol) of 3-bromopropionyl chloride in 100 ml of anhydrous benzene was added dropwise with stirring a solution of 8.6 g (0.10 mol) of anhydrous piperazine in 20 ml of dry chloroform over a period of 30 minutes. The temperature rose spontaneously to 45°C during the addition. After the temperature ceased to rise, stirring was continued for another hour. The reaction mixture was then filtered to remove the piperazine hydrochloride by-product. The filtrate was evaporated to dryness and the residue recrystallized from ethanol to obtain the desired N,N'-bis-(3bromopropionyl)piperazine as a white crystalline solid melting at 103°C to 104°C. The identity of the product was further established by elemental analysis.

Brand name

Vercyte (Abbott).

Therapeutic Function

Antineoplastic

Safety Profile

Poison by ingestion,subcutaneous and intraperitoneal routes. An experimentalteratogen. Other experimental reproductive effects.Human mutation data reported. When heated todecomposition it emits very toxic fumes of Br- and NOx.
InChI:InChI=1/C10H16Br2N2O2/c11-3-1-9(15)13-5-7-14(8-6-13)10(16)2-4-12/h1-8H2

54-91-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,1'-(Piperazine-1,4-diyl)bis(3-bromopropan-1-one)

1.2 Other means of identification

Product number -
Other names Pipobroman

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:54-91-1 SDS

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