540-73-8 Usage
Chemical Properties
Different sources of media describe the Chemical Properties of 540-73-8 differently. You can refer to the following data:
1. colourless or yellow hygroscopic liquid which fumes in air
2. 1,2-Dimethylhydrazine is a colorless or yellow hygroscopic liquid and releases fumes in
air. 1,2-Dimethylhydrazine is stable and incompatible with oxidizing agents, water, and
moisture. Hydrazines include 1,1-dimethylhydrazine and 1,2-dimethylhydrazine, collectively.
Hydrazines in pure form are clear, colorless liquids that quickly evaporate in air.
Hydrazines smell somewhat like ammonia. Hydrazines are highly reactive and easily catch
fi re. 1,1-Dimethylhydrazine, and 1,2-dimethylhydrazine are somewhat similar in chemical
structure and reactivity. However, there are some clear differences in their production,
uses, and adverse health effects. There are many other hydrazine compounds. Hydrazines
are manufactured from chemicals such as ammonia, dimethylamine, hydrogen perox-
ide, and sodium hypochlorite. A small amount of hydrazine occurs naturally in some
plants. Large amounts of hydrazines are in different countries. 1,2-Dimethylhydrazine is a
research chemical and the quantities produced are likely to be much less.
Hydrazine has been used as a fuel source for rocket propellant and spacecraft, including
the space shuttle. Hydrazine is also used to treat boiler water to reduce corrosion and to
reduce other chemical substances. Hydrazine is used as a medicine and in the manufacture
of other medicines, farm chemicals, and plastic foams. 1,1-Dimethylhydrazine has been
used as a rocket propellant and in the manufacture of other chemical substances, while
the literature indicate that 1,2-dimethylhydrazine has no commercial use but is used in
researches to study colon cancer in experimental animals.
Uses
1,2-Dimethylhydrazine (SDMH) unlike its analog 1,1-
dimethylhydrazine (UDMH) is used only in small quantities
as a research chemical. There are no known commercial uses,
although it was evaluated as a high-energy rocket fuel. The
material is a fuming, strongly alkaline, moderately volatile
liquid.
Definition
ChEBI: A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
General Description
A colorless liquid with an ammonia-like odor. Less dense than water. Flash point is 5°F. Contact irritate skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Used to make photographic chemicals.
Air & Water Reactions
Highly flammable. Fumes upon exposure to air . Soluble in water with evolution of heat.
Reactivity Profile
1，2-Dimethyl hydrazine dissolves, swells, and disintegrates many plastics [USCG, 1999].
Health Hazard
Different sources of media describe the Health Hazard of 540-73-8 differently. You can refer to the following data:
1. Breathing of vapor causes pulmonary irritation, delayed gastro-intestinal irritation, tremors, and convulsions. Contact with skin or mucous membranes causes chemical burns. Can be absorbed through skin to cause systemic intoxication and convulsions.
2. Inhalation exposure to hydrazines, cause adverse health effects and poisoning to animals
and humans. The symptoms of toxicity and poisoning include, but are not limited to,
injury to the lungs, liver, kidney, vomiting, uncontrolled shaking, lethargy (sluggishness),
coma, and neuritis (an infl ammation of the nerves), convulsions, tremors, seizures, and the
CNS. Effects on the nervous system have also been seen in animals exposed to hydrazine
and 1,1-dimethylhydrazine, but not to 1,2-dimethylhydrazine.
Safety Profile
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by ingestion, intraperitoneal,
intravenous, subcutaneous, and
intramuscular routes. Moderately toxic by
inhalation. Human mutation data reported.
A very dangerous fire hazard when exposedto heat, flame, or oxidizers. A hgh-energy
propellant for liquid-fueled rockets. When
heated to decomposition it emits toxic
fumes of NOx
Carcinogenicity
SDMH is carcinogenic to mice,
rats, and hamsters using a variety of exposure routes. Oral
doses of 21 mg/kg for 11 weeks produced intestinal tumors
in rats. A lower dose (3 mg/kg) in drinking water for
12 months produced liver hemangioendotheliomas.A
number of these tumors were metastatic. Mice given
doses of 60–90 mg/day in drinking water developed a variety
of tumors including angiosarcomas and lung adenomas
. Both oral administration and intraperitoneal
injection increased lung adenomas in the A/J strain
mouse. Hamsters also developed angiosarcomas,
intestinal tumors, and liver tumors following average daily
intakes of 160 mg in drinking water. An in-depth
description of the uniqueness of the colonic tumors was
presented.
Check Digit Verification of cas no
The CAS Registry Mumber 540-73-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 540-73:
(5*5)+(4*4)+(3*0)+(2*7)+(1*3)=58
58 % 10 = 8
So 540-73-8 is a valid CAS Registry Number.
This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.