54006-61-0Relevant academic research and scientific papers
Synthesis of Some Hydrazone and Pyrazoline Derivatives
Faidallah, Hassan M.,Mokhtar, Hassan M.,Nassar, Ahmed,Ahmed, Mohamed M.
, p. 179 - 181 (2007/10/03)
Condensation of chalcones (1) with aroyl- and arylhydrazines afforded the corresponding hydrazones (2 and 3), cyclization of the hydrazones (3) with HCl gave the pyrazoline derivatives (4) which on oxidation with bromine water yielded the corresponding pyrazoles (5).Addition of 5-p-bromophenyl-3-methyl-1-p-sulphamylphenylpyrazole (5c) to allylisothiocyanate afforded the thiourea derivative (6) which was readily cyclized with ethyl bromoacetate to the corresponding oxothiazolidine (7). - Key Words: Hydrazones; Pyrazolines; Preparation.
