5401-50-3 Usage
Description
N-benzyl-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a pyrazolopyrimidine derivative with potential biological and pharmacological activities. It features a benzyl, methyl, and phenyl group attached to the pyrazolopyrimidine core structure, which may contribute to its potential as an anticancer agent and kinase inhibitor.
Uses
Used in Pharmaceutical Industry:
N-benzyl-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine is used as a potential anticancer agent for its ability to inhibit the growth of cancer cells. It has shown promising results in this area, making it a candidate for further research and development in cancer treatment.
Used in Medicinal Chemistry Research:
N-benzyl-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine is also used as a kinase inhibitor, which may have implications for the treatment of various diseases and conditions. Its activity in this area highlights its potential for further exploration in medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 5401-50-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,0 and 1 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5401-50:
(6*5)+(5*4)+(4*0)+(3*1)+(2*5)+(1*0)=63
63 % 10 = 3
So 5401-50-3 is a valid CAS Registry Number.
5401-50-3Relevant articles and documents
Synthesis of novel 2-alkyl-4-substituted-amino-pyrazolo[3,4-d]pyrimidines as new leads for anti-bacterial and anti-cancer activity
Devarakonda, Murty,Doonaboina, Raghava,Vanga, Sreedher,Vemu, Jahnavi,Boni, Sathoshini,Mailavaram, Raghu Prasad
, p. 1090 - 1101 (2013/04/10)
Treatment of 6-alkyl-1-phenyl-4-chloro-(1H)-pyrazolo[3,4-d]pyrimidines, with different amines afforded a series of compounds whose identity and purity were confirmed by spectral and analytical means. The compounds were tested for antibacterial activity against four organisms viz. Staphylococcus aureus (Gram positive), S. epidermidis (Gram positive), Bacillus subtilis (Gram positive), Escherichia coli (Gram negative) using amoxicillin as standard control. Compounds 4d, 6b, 6c have shown best antibacterial activity in the series. The antiproliferative activity was tested against human skin cancer cell line G361. The compounds 3d, 4d, 5b, 5d, 5e, 6c, 7a were found to be the best of the series and showed the activity at micromolar concentration.
